An update on the evaluation and management of small pulmonary nodules

Future Oncol. 2013 Jun;9(6):855-65. doi: 10.2217/fon.13.17.

Abstract

The widespread utilization of chest CT scans has increased the importance of the proper evaluation of incidentally found lung nodules. The primary goal in the evaluation of these nodules is to determine whether they are malignant or benign. Clinical factors such as older age, tobacco smoking, and current or remote history of malignancy increase the pretest likelihood of malignancy. Radiological features of these nodules are important in differentiating benign from malignant lesions. However, the etiology of the lung nodules frequently remains indeterminate and requires further evaluation. The approach to the management of indeterminate lung nodules ranges between observation with repeat chest CT scan, further diagnostic studies such as PET scan or invasive procedures to obtain tissue diagnosis. This article reviews the importance of the different radiological features of lung nodules. This is followed by an update on the approach to the management of the different types of small lung nodules.

Publication types

  • Review

MeSH terms

  • Aging
  • Calcinosis / diagnostic imaging
  • Calcinosis / pathology
  • Humans
  • Lung Neoplasms / diagnostic imaging
  • Lung Neoplasms / pathology*
  • Lung Neoplasms / surgery
  • Lung Neoplasms / therapy
  • Multimodal Imaging / methods*
  • Positron-Emission Tomography*
  • Radiography, Thoracic / methods
  • Risk Factors
  • Smoking
  • Solitary Pulmonary Nodule / diagnostic imaging
  • Solitary Pulmonary Nodule / pathology*
  • Solitary Pulmonary Nodule / surgery
  • Solitary Pulmonary Nodule / therapy
  • Tomography, X-Ray Computed*