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Inhibition of radiation-induced EGFR nuclear import by C225 (Cetuximab) suppresses DNA-PK activity.
Dittmann K, Mayer C, Rodemann HP. Dittmann K, et al. Radiother Oncol. 2005 Aug;76(2):157-61. doi: 10.1016/j.radonc.2005.06.022. Radiother Oncol. 2005. PMID: 16024112
Bowman-Birk proteinase inhibitor (BBI) modulates radiosensitivity and radiation-induced differentiation of human fibroblasts in culture.
Dittmann K, Löffler H, Bamberg M, Rodemann HP. Dittmann K, et al. Radiother Oncol. 1995 Feb;34(2):137-43. doi: 10.1016/0167-8140(94)01494-n. Radiother Oncol. 1995. PMID: 7597212
Bowman-Birk protease inhibitor reduces the radiation-induced activation of the EGF receptor and induces tyrosine phosphatase activity.
Gueven N, Dittmann K, Mayer C, Rodemann HP. Gueven N, et al. Among authors: dittmann k. Int J Radiat Biol. 1998 Feb;73(2):157-62. doi: 10.1080/095530098142536. Int J Radiat Biol. 1998. PMID: 9489562
The radioprotective potential of the Bowman-Birk protease inhibitor is independent of its secondary structure.
Gueven N, Dittmann K, Mayer C, Rodemann HP. Gueven N, et al. Among authors: dittmann k. Cancer Lett. 1998 Mar 13;125(1-2):77-82. doi: 10.1016/s0304-3835(97)00481-3. Cancer Lett. 1998. PMID: 9566699
MK-886, a leukotriene biosynthesis inhibitor, induces antiproliferative effects and apoptosis in HL-60 cells.
Dittmann KH, Mayer C, Rodemann HP, Petrides PE, Denzlinger C. Dittmann KH, et al. Leuk Res. 1998 Jan;22(1):49-53. doi: 10.1016/s0145-2126(97)00132-x. Leuk Res. 1998. PMID: 9585079
The radioprotective effect of BBI is associated with the activation of DNA repair-relevant genes.
Dittmann KH, Gueven N, Mayer C, Rodemann HP. Dittmann KH, et al. Int J Radiat Biol. 1998 Aug;74(2):225-30. doi: 10.1080/095530098141609. Int J Radiat Biol. 1998. PMID: 9712551
The presence of wild-type TP53 is necessary for the radioprotective effect of the Bowman-Birk proteinase inhibitor in normal fibroblasts.
Dittmann KH, Gueven N, Mayer C, Ohneseit P, Zell R, Begg AC, Rodemann HP. Dittmann KH, et al. Radiat Res. 1998 Dec;150(6):648-55. Radiat Res. 1998. PMID: 9840184
The Bowman-Birk protease inhibitor enhances clonogenic cell survival of ionizing radiation-treated nucleotide excision repair-competent cells but not of xeroderma pigmentosum cells.
Dittmann KH, Dikomey E, Mayer C, Rodemann HP. Dittmann KH, et al. Int J Radiat Biol. 2000 Feb;76(2):223-9. doi: 10.1080/095530000138871. Int J Radiat Biol. 2000. PMID: 10716643
Characterization of the amino acids essential for the photo- and radioprotective effects of a Bowman-Birk protease inhibitor-derived nonapeptide.
Dittmann KH, Gueven N, Mayer C, Rodemann HP. Dittmann KH, et al. Protein Eng. 2001 Mar;14(3):157-60. doi: 10.1093/protein/14.3.157. Protein Eng. 2001. PMID: 11342711
Bowman-Birk proteinase inhibitor-mediated radioprotection against UV irradiation is TP53-dependent and associated with stimulation of nucleotide excision repair.
Dittmann K, Knaus-Dittmann D, Mayer C, Rodemann HP. Dittmann K, et al. Radiat Environ Biophys. 2001 Jun;40(2):163-7. doi: 10.1007/s004110100091. Radiat Environ Biophys. 2001. PMID: 11484788
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