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The epidermal growth factor receptor and its ligands as therapeutic targets in human tumors.
Rusch V, Mendelsohn J, Dmitrovsky E. Rusch V, et al. Among authors: dmitrovsky e. Cytokine Growth Factor Rev. 1996 Aug;7(2):133-41. doi: 10.1016/1359-6101(96)00016-0. Cytokine Growth Factor Rev. 1996. PMID: 8899291 Review.
Aberrant p53 expression predicts clinical resistance to cisplatin-based chemotherapy in locally advanced non-small cell lung cancer.
Rusch V, Klimstra D, Venkatraman E, Oliver J, Martini N, Gralla R, Kris M, Dmitrovsky E. Rusch V, et al. Among authors: dmitrovsky e. Cancer Res. 1995 Nov 1;55(21):5038-42. Cancer Res. 1995. PMID: 7585548
Evidence for the epidermal growth factor receptor as a target for lung cancer prevention.
Lonardo F, Dragnev KH, Freemantle SJ, Ma Y, Memoli N, Sekula D, Knauth EA, Beebe JS, Dmitrovsky E. Lonardo F, et al. Among authors: dmitrovsky e. Clin Cancer Res. 2002 Jan;8(1):54-60. Clin Cancer Res. 2002. PMID: 11801540
Wnt pathway reprogramming during human embryonal carcinoma differentiation and potential for therapeutic targeting.
Snow GE, Kasper AC, Busch AM, Schwarz E, Ewings KE, Bee T, Spinella MJ, Dmitrovsky E, Freemantle SJ. Snow GE, et al. Among authors: dmitrovsky e. BMC Cancer. 2009 Oct 29;9:383. doi: 10.1186/1471-2407-9-383. BMC Cancer. 2009. PMID: 19874621 Free PMC article.
Epidermal growth factor receptor tyrosine kinase inhibition represses cyclin D1 in aerodigestive tract cancers.
Petty WJ, Dragnev KH, Memoli VA, Ma Y, Desai NB, Biddle A, Davis TH, Nugent WC, Memoli N, Hamilton M, Iwata KK, Rigas JR, Dmitrovsky E. Petty WJ, et al. Among authors: dmitrovsky e. Clin Cancer Res. 2004 Nov 15;10(22):7547-54. doi: 10.1158/1078-0432.CCR-04-1169. Clin Cancer Res. 2004. PMID: 15569985
all-trans retinoic acid for treating germ cell tumors. In vitro activity and results of a phase II trial.
Moasser MM, Motzer RJ, Khoo KS, Lyn P, Murphy BA, Bosl GJ, Dmitrovsky E. Moasser MM, et al. Among authors: dmitrovsky e. Cancer. 1995 Aug 15;76(4):680-6. doi: 10.1002/1097-0142(19950815)76:4<680::aid-cncr2820760423>3.0.co;2-9. Cancer. 1995. PMID: 8625166 Clinical Trial.
Derivation and characterization of retinoid-resistant human embryonal carcinoma cells.
Moasser MM, Khoo KS, Maerz WJ, Zelenetz A, Dmitrovsky E. Moasser MM, et al. Among authors: dmitrovsky e. Differentiation. 1996 Jul;60(4):251-7. doi: 10.1046/j.1432-0436.1996.6040251.x. Differentiation. 1996. PMID: 8765055
Cyclin D1 proteolysis: a retinoid chemoprevention signal in normal, immortalized, and transformed human bronchial epithelial cells.
Boyle JO, Langenfeld J, Lonardo F, Sekula D, Reczek P, Rusch V, Dawson MI, Dmitrovsky E. Boyle JO, et al. Among authors: dmitrovsky e. J Natl Cancer Inst. 1999 Feb 17;91(4):373-9. doi: 10.1093/jnci/91.4.373. J Natl Cancer Inst. 1999. PMID: 10050872
We also examined whether calpain inhibitor I, an inhibitor of the 26S proteasome degradation pathway, affected the decline (i.e., proteolysis) of cyclin D1. ...
We also examined whether calpain inhibitor I, an inhibitor of the 26S proteasome degradation pathway, affected the decline (i.e., pro …
Targeting the PML/RAR alpha translocation product triggers apoptosis in promyelocytic leukemia cells.
Nason-Burchenal K, Takle G, Pace U, Flynn S, Allopenna J, Martin P, George ST, Goldberg AR, Dmitrovsky E. Nason-Burchenal K, et al. Among authors: dmitrovsky e. Oncogene. 1998 Oct 8;17(14):1759-68. doi: 10.1038/sj.onc.1202075. Oncogene. 1998. PMID: 9778041
Targeting of PML/RARalpha is lethal to retinoic acid-resistant promyelocytic leukemia cells.
Nason-Burchenal K, Allopenna J, Bègue A, Stéhelin D, Dmitrovsky E, Martin P. Nason-Burchenal K, et al. Among authors: dmitrovsky e. Blood. 1998 Sep 1;92(5):1758-67. Blood. 1998. PMID: 9716606
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