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Therapeutic advances in amyotrophic lateral sclerosis.
Louvel E, Hugon J, Doble A. Louvel E, et al. Among authors: doble a. Trends Pharmacol Sci. 1997 Jun;18(6):196-203. doi: 10.1016/s0165-6147(97)01062-6. Trends Pharmacol Sci. 1997. PMID: 9226998 Review.
Amyotrophic lateral sclerosis (ALS) is a progressive and rapidly fatal neurodegenerative disease in which both upper and lower motoneurones are involved. The recent discovery of mutations affecting the superoxide dismutase (SOD) gene has given impetus to research on the ro …
Amyotrophic lateral sclerosis (ALS) is a progressive and rapidly fatal neurodegenerative disease in which both upper and lower motone …
Riluzole series. Synthesis and in vivo "antiglutamate" activity of 6-substituted-2-benzothiazolamines and 3-substituted-2-imino-benzothiazolines.
Jimonet P, Audiau F, Barreau M, Blanchard JC, Boireau A, Bour Y, Coléno MA, Doble A, Doerflinger G, Huu CD, Donat MH, Duchesne JM, Ganil P, Guérémy C, Honor E, Just B, Kerphirique R, Gontier S, Hubert P, Laduron PM, Le Blevec J, Meunier M, Miquet JM, Nemecek C, Mignani S, et al. Jimonet P, et al. Among authors: doble a. J Med Chem. 1999 Jul 29;42(15):2828-43. doi: 10.1021/jm980202u. J Med Chem. 1999. PMID: 10425092
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