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Dysregulation of Nutrient Sensing and CLEARance in Presenilin Deficiency.
Reddy K, Cusack CL, Nnah IC, Khayati K, Saqcena C, Huynh TB, Noggle SA, Ballabio A, Dobrowolski R. Reddy K, et al. Among authors: dobrowolski r. Cell Rep. 2016 Mar 8;14(9):2166-2179. doi: 10.1016/j.celrep.2016.02.006. Epub 2016 Feb 25. Cell Rep. 2016. PMID: 26923592 Free PMC article.
Amino acid metabolites, mTORC1 and aging.
Antikainen H, Khayati K, Dobrowolski R. Antikainen H, et al. Among authors: dobrowolski r. Aging (Albany NY). 2017 Jul 17;9(7):1641-1642. doi: 10.18632/aging.101266. Aging (Albany NY). 2017. PMID: 28722657 Free PMC article. No abstract available.
TOR-mediated regulation of metabolism in aging.
Antikainen H, Driscoll M, Haspel G, Dobrowolski R. Antikainen H, et al. Among authors: dobrowolski r. Aging Cell. 2017 Dec;16(6):1219-1233. doi: 10.1111/acel.12689. Epub 2017 Oct 2. Aging Cell. 2017. PMID: 28971552 Free PMC article. Review.
The connexin 40 A96S mutation causes renin-dependent hypertension.
Lübkemeier I, Machura K, Kurtz L, Neubauer B, Dobrowolski R, Schweda F, Wagner C, Willecke K, Kurtz A. Lübkemeier I, et al. Among authors: dobrowolski r. J Am Soc Nephrol. 2011 Jun;22(6):1031-40. doi: 10.1681/ASN.2010101047. Epub 2011 May 19. J Am Soc Nephrol. 2011. PMID: 21597036 Free PMC article.
The amino acid metabolite homocysteine activates mTORC1 to inhibit autophagy and form abnormal proteins in human neurons and mice.
Khayati K, Antikainen H, Bonder EM, Weber GF, Kruger WD, Jakubowski H, Dobrowolski R. Khayati K, et al. Among authors: dobrowolski r. FASEB J. 2017 Feb;31(2):598-609. doi: 10.1096/fj.201600915R. Epub 2016 Oct 25. FASEB J. 2017. PMID: 28148781
., Bonder, E. M., Weber, G. F., Kruger, W. D., Jakubowski, H., Dobrowolski, R. The amino acid metabolite homocysteine activates mTORC1 to inhibit autophagy and form abnormal proteins in human neurons and mice....
., Bonder, E. M., Weber, G. F., Kruger, W. D., Jakubowski, H., Dobrowolski, R. The amino acid metabolite homocysteine activate …
TFEB-driven endocytosis coordinates MTORC1 signaling and autophagy.
Nnah IC, Wang B, Saqcena C, Weber GF, Bonder EM, Bagley D, De Cegli R, Napolitano G, Medina DL, Ballabio A, Dobrowolski R. Nnah IC, et al. Among authors: dobrowolski r. Autophagy. 2019 Jan;15(1):151-164. doi: 10.1080/15548627.2018.1511504. Epub 2018 Sep 10. Autophagy. 2019. PMID: 30145926 Free PMC article.
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