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RNA polymerase III limits longevity downstream of TORC1.
Filer D, Thompson MA, Takhaveev V, Dobson AJ, Kotronaki I, Green JWM, Heinemann M, Tullet JMA, Alic N. Filer D, et al. Among authors: dobson aj. Nature. 2017 Dec 14;552(7684):263-267. doi: 10.1038/nature25007. Epub 2017 Nov 29. Nature. 2017. PMID: 29186112 Free PMC article.
Longevity is determined by ETS transcription factors in multiple tissues and diverse species.
Dobson AJ, Boulton-McDonald R, Houchou L, Svermova T, Ren Z, Subrini J, Vazquez-Prada M, Hoti M, Rodriguez-Lopez M, Ibrahim R, Gregoriou A, Gkantiragas A, Bähler J, Ezcurra M, Alic N. Dobson AJ, et al. PLoS Genet. 2019 Jul 29;15(7):e1008212. doi: 10.1371/journal.pgen.1008212. eCollection 2019 Jul. PLoS Genet. 2019. PMID: 31356597 Free PMC article.
The neuronal receptor tyrosine kinase Alk is a target for longevity.
Woodling NS, Aleyakpo B, Dyson MC, Minkley LJ, Rajasingam A, Dobson AJ, Leung KHC, Pomposova S, Fuentealba M, Alic N, Partridge L. Woodling NS, et al. Among authors: dobson aj. Aging Cell. 2020 May;19(5):e13137. doi: 10.1111/acel.13137. Epub 2020 Apr 15. Aging Cell. 2020. PMID: 32291952 Free PMC article.
330 results