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The folding of hen lysozyme involves partially structured intermediates and multiple pathways.
Radford SE, Dobson CM, Evans PA. Radford SE, et al. Among authors: dobson cm. Nature. 1992 Jul 23;358(6384):302-7. doi: 10.1038/358302a0. Nature. 1992. PMID: 1641003
Thermal unfolding of an intermediate is associated with non-Arrhenius kinetics in the folding of hen lysozyme.
Matagne A, Jamin M, Chung EW, Robinson CV, Radford SE, Dobson CM. Matagne A, et al. Among authors: dobson cm. J Mol Biol. 2000 Mar 17;297(1):193-210. doi: 10.1006/jmbi.2000.3540. J Mol Biol. 2000. PMID: 10704316
Side-chain conformations in an unfolded protein: chi1 distributions in denatured hen lysozyme determined by heteronuclear 13C, 15N NMR spectroscopy.
Hennig M, Bermel W, Spencer A, Dobson CM, Smith LJ, Schwalbe H. Hennig M, et al. Among authors: dobson cm. J Mol Biol. 1999 May 14;288(4):705-23. doi: 10.1006/jmbi.1999.2722. J Mol Biol. 1999. PMID: 10329174
Side-chain conformational disorder in a molten globule: molecular dynamics simulations of the A-state of human alpha-lactalbumin.
Smith LJ, Dobson CM, van Gunsteren WF. Smith LJ, et al. Among authors: dobson cm. J Mol Biol. 1999 Mar 12;286(5):1567-80. doi: 10.1006/jmbi.1999.2545. J Mol Biol. 1999. PMID: 10064716
Structural characterization of the transition state for folding of muscle acylphosphatase.
Chiti F, Taddei N, van Nuland NA, Magherini F, Stefani M, Ramponi G, Dobson CM. Chiti F, et al. Among authors: dobson cm. J Mol Biol. 1998 Nov 6;283(4):893-903. doi: 10.1006/jmbi.1998.2010. J Mol Biol. 1998. PMID: 9790847
Protein subunit interactions and structural integrity of amyloidogenic transthyretins: evidence from electrospray mass spectrometry.
Nettleton EJ, Sunde M, Lai Z, Kelly JW, Dobson CM, Robinson CV. Nettleton EJ, et al. Among authors: dobson cm. J Mol Biol. 1998 Aug 21;281(3):553-64. doi: 10.1006/jmbi.1998.1937. J Mol Biol. 1998. PMID: 9698569
Molecular dynamics simulations of peptide fragments from hen lysozyme: insight into non-native protein conformations.
Smith LJ, Mark AE, Dobson CM, van Gunsteren WF. Smith LJ, et al. Among authors: dobson cm. J Mol Biol. 1998 Jul 24;280(4):703-19. doi: 10.1006/jmbi.1998.1892. J Mol Biol. 1998. PMID: 9677298
The origin of the alpha-domain intermediate in the folding of hen lysozyme.
Matagne A, Chung EW, Ball LJ, Radford SE, Robinson CV, Dobson CM. Matagne A, et al. Among authors: dobson cm. J Mol Biol. 1998 Apr 17;277(5):997-1005. doi: 10.1006/jmbi.1998.1657. J Mol Biol. 1998. PMID: 9571017
A comparison of the folding kinetics and thermodynamics of two homologous fibronectin type III modules.
Plaxco KW, Spitzfaden C, Campbell ID, Dobson CM. Plaxco KW, et al. Among authors: dobson cm. J Mol Biol. 1997 Aug 1;270(5):763-70. doi: 10.1006/jmbi.1997.1148. J Mol Biol. 1997. PMID: 9245603
Fast and slow tracks in lysozyme folding: insight into the role of domains in the folding process.
Matagne A, Radford SE, Dobson CM. Matagne A, et al. Among authors: dobson cm. J Mol Biol. 1997 Apr 18;267(5):1068-74. doi: 10.1006/jmbi.1997.0963. J Mol Biol. 1997. PMID: 9150396
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