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Human SH2B1 mutations are associated with maladaptive behaviors and obesity.
J Clin Invest. 2012 Dec;122(12):4732-6. doi: 10.1172/JCI62696. Epub 2012 Nov 19.
J Clin Invest. 2012.
PMID: 23160192
Free PMC article.
Functional characterization of obesity-associated variants involving the α and β isoforms of human SH2B1.
Pearce LR, Joe R, Doche ME, Su HW, Keogh JM, Henning E, Argetsinger LS, Bochukova EG, Cline JM, Garg S, Saeed S, Shoelson S, O'Rahilly S, Barroso I, Rui L, Farooqi IS, Carter-Su C.
Pearce LR, et al. Among authors: doche me.
Endocrinology. 2014 Sep;155(9):3219-26. doi: 10.1210/en.2014-1264. Epub 2014 Jun 27.
Endocrinology. 2014.
PMID: 24971614
Free PMC article.
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Phosphorylation of the Unique C-Terminal Tail of the Alpha Isoform of the Scaffold Protein SH2B1 Controls the Ability of SH2B1α To Enhance Nerve Growth Factor Function.
Joe RM, Flores A, Doche ME, Cline JM, Clutter ES, Vander PB, Riedel H, Argetsinger LS, Carter-Su C.
Joe RM, et al. Among authors: doche me.
Mol Cell Biol. 2018 Feb 27;38(6):e00277-17. doi: 10.1128/MCB.00277-17. Print 2018 Mar 15.
Mol Cell Biol. 2018.
PMID: 29229648
Free PMC article.
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The nucleolar δ isoform of adapter protein SH2B1 enhances morphological complexity and function of cultured neurons.
Cote JL, Vander PB, Ellis M, Cline JM, Svezhova N, Doche ME, Maures TJ, Choudhury TA, Kong S, Klaft OGJ, Joe RM, Argetsinger LS, Carter-Su C.
Cote JL, et al. Among authors: doche me.
J Cell Sci. 2022 Feb 1;135(3):jcs259179. doi: 10.1242/jcs.259179. Epub 2022 Feb 10.
J Cell Sci. 2022.
PMID: 35019135
Free PMC article.
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Anti-EGFR Therapy Induces EGF Secretion by Cancer-Associated Fibroblasts to Confer Colorectal Cancer Chemoresistance.
Garvey CM, Lau R, Sanchez A, Sun RX, Fong EJ, Doche ME, Chen O, Jusuf A, Lenz HJ, Larson B, Mumenthaler SM.
Garvey CM, et al. Among authors: doche me.
Cancers (Basel). 2020 May 28;12(6):1393. doi: 10.3390/cancers12061393.
Cancers (Basel). 2020.
PMID: 32481658
Free PMC article.
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Data integration from pathology slides for quantitative imaging of multiple cell types within the tumor immune cell infiltrate.
Ma Z, Shiao SL, Yoshida EJ, Swartwood S, Huang F, Doche ME, Chung AP, Knudsen BS, Gertych A.
Ma Z, et al. Among authors: doche me.
Diagn Pathol. 2017 Sep 18;12(1):69. doi: 10.1186/s13000-017-0658-8.
Diagn Pathol. 2017.
PMID: 28923066
Free PMC article.
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Hepatic Tm6sf2 overexpression affects cellular ApoB-trafficking, plasma lipid levels, hepatic steatosis and atherosclerosis.
Ehrhardt N, Doche ME, Chen S, Mao HZ, Walsh MT, Bedoya C, Guindi M, Xiong W, Ignatius Irudayam J, Iqbal J, Fuchs S, French SW, Mahmood Hussain M, Arditi M, Arumugaswami V, Péterfy M.
Ehrhardt N, et al. Among authors: doche me.
Hum Mol Genet. 2017 Jul 15;26(14):2719-2731. doi: 10.1093/hmg/ddx159.
Hum Mol Genet. 2017.
PMID: 28449094
Free PMC article.
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