Doctor BP - Search Results

1

Pretreatment with human serum butyrylcholinesterase alone prevents cardiac abnormalities, seizures, and death in Göttingen minipigs exposed to sarin vapor.

Saxena A, Sun W, Dabisch PA, Hulet SW, Hastings NB, Jakubowski EM, Mioduszewski RJ, Doctor BP. Saxena A, et al. Among authors: doctor bp. Biochem Pharmacol. 2011 Dec 15;82(12):1984-93. doi: 10.1016/j.bcp.2011.09.019. Epub 2011 Sep 24. Biochem Pharmacol. 2011. PMID: 21968035

2

Human serum butyrylcholinesterase: in vitro and in vivo stability, pharmacokinetics, and safety in mice.

Saxena A, Sun W, Luo C, Doctor BP. Saxena A, et al. Among authors: doctor bp. Chem Biol Interact. 2005 Dec 15;157-158:199-203. doi: 10.1016/j.cbi.2005.10.028. Epub 2005 Nov 2. Chem Biol Interact. 2005. PMID: 16263104

3

A repeated injection of polyethyleneglycol-conjugated recombinant human butyrylcholinesterase elicits immune response in mice.

Chilukuri N, Sun W, Parikh K, Naik RS, Tang L, Doctor BP, Saxena A. Chilukuri N, et al. Among authors: doctor bp. Toxicol Appl Pharmacol. 2008 Sep 15;231(3):423-9. doi: 10.1016/j.taap.2008.05.016. Epub 2008 May 28. Toxicol Appl Pharmacol. 2008. PMID: 18586293

4

Efficacy of human serum butyrylcholinesterase against sarin vapor.

Saxena A, Sun W, Dabisch PA, Hulet SW, Hastings NB, Jakubowski EM, Mioduszewski RJ, Doctor BP. Saxena A, et al. Among authors: doctor bp. Chem Biol Interact. 2008 Sep 25;175(1-3):267-72. doi: 10.1016/j.cbi.2008.05.022. Epub 2008 May 23. Chem Biol Interact. 2008. PMID: 18597747

5

Long-term effects of human butyrylcholinesterase pretreatment followed by acute soman challenge in cynomolgus monkeys.

Sun W, Doctor BP, Lenz DE, Saxena A. Sun W, et al. Among authors: doctor bp. Chem Biol Interact. 2008 Sep 25;175(1-3):428-30. doi: 10.1016/j.cbi.2008.04.036. Epub 2008 May 3. Chem Biol Interact. 2008. PMID: 18674756

6

Safety of administration of human butyrylcholinesterase and its conjugates with soman or VX in rats.

Genovese RF, Sun W, Johnson CC, Ditargiani RC, Doctor BP, Saxena A. Genovese RF, et al. Among authors: doctor bp. Basic Clin Pharmacol Toxicol. 2010 May;106(5):428-34. doi: 10.1111/j.1742-7843.2009.00508.x. Epub 2009 Dec 29. Basic Clin Pharmacol Toxicol. 2010. PMID: 20050840 Free article.

7

Prophylaxis with human serum butyrylcholinesterase protects guinea pigs exposed to multiple lethal doses of soman or VX.

Saxena A, Sun W, Fedorko JM, Koplovitz I, Doctor BP. Saxena A, et al. Among authors: doctor bp. Biochem Pharmacol. 2011 Jan 1;81(1):164-9. doi: 10.1016/j.bcp.2010.09.007. Epub 2010 Sep 21. Biochem Pharmacol. 2011. PMID: 20846507

8

Effect of polyethylene glycol conjugation on the circulatory stability of plasma-derived human butyrylcholinesterase in mice.

Sun W, Luo C, Tipparaju P, Doctor BP, Saxena A. Sun W, et al. Among authors: doctor bp. Chem Biol Interact. 2013 Mar 25;203(1):172-6. doi: 10.1016/j.cbi.2012.11.021. Epub 2012 Dec 7. Chem Biol Interact. 2013. PMID: 23220586

9

Prophylaxis with human serum butyrylcholinesterase protects Göttingen minipigs exposed to a lethal high-dose of sarin vapor.

Saxena A, Hastings NB, Sun W, Dabisch PA, Hulet SW, Jakubowski EM, Mioduszewski RJ, Doctor BP. Saxena A, et al. Among authors: doctor bp. Chem Biol Interact. 2015 Aug 5;238:161-9. doi: 10.1016/j.cbi.2015.07.001. Epub 2015 Jul 3. Chem Biol Interact. 2015. PMID: 26145887

10

Safety and pharmacokinetics of human serum butyrylcholinesterase in guinea pigs.

Sun W, Doctor BP, Saxena A. Sun W, et al. Among authors: doctor bp. Chem Biol Interact. 2005 Dec 15;157-158:428-9. doi: 10.1016/j.cbi.2005.10.090. Chem Biol Interact. 2005. PMID: 16429577

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