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Biomarkers are here to stay for clinical research and standard care.
Bunn PA Jr, Hirsch FR, Doebele RC, Camidge DR, Varella-Garcia M, Franklin W. Bunn PA Jr, et al. Among authors: doebele rc. J Thorac Oncol. 2010 Aug;5(8):1113-5. doi: 10.1097/JTO.0b013e3181e7616e. J Thorac Oncol. 2010. PMID: 20661083 Free article. No abstract available.
Optimizing the detection of lung cancer patients harboring anaplastic lymphoma kinase (ALK) gene rearrangements potentially suitable for ALK inhibitor treatment.
Camidge DR, Kono SA, Flacco A, Tan AC, Doebele RC, Zhou Q, Crino L, Franklin WA, Varella-Garcia M. Camidge DR, et al. Among authors: doebele rc. Clin Cancer Res. 2010 Nov 15;16(22):5581-90. doi: 10.1158/1078-0432.CCR-10-0851. Epub 2010 Nov 9. Clin Cancer Res. 2010. PMID: 21062932 Free PMC article.
Genetic testing for lung cancer: reflex versus clinical selection.
Bunn PA Jr, Doebele RC. Bunn PA Jr, et al. Among authors: doebele rc. J Clin Oncol. 2011 May 20;29(15):1943-5. doi: 10.1200/JCO.2010.34.1974. Epub 2011 Apr 11. J Clin Oncol. 2011. PMID: 21483017 Free PMC article. No abstract available.
Effect of crizotinib on overall survival in patients with advanced non-small-cell lung cancer harbouring ALK gene rearrangement: a retrospective analysis.
Shaw AT, Yeap BY, Solomon BJ, Riely GJ, Gainor J, Engelman JA, Shapiro GI, Costa DB, Ou SH, Butaney M, Salgia R, Maki RG, Varella-Garcia M, Doebele RC, Bang YJ, Kulig K, Selaru P, Tang Y, Wilner KD, Kwak EL, Clark JW, Iafrate AJ, Camidge DR. Shaw AT, et al. Among authors: doebele rc. Lancet Oncol. 2011 Oct;12(11):1004-12. doi: 10.1016/S1470-2045(11)70232-7. Epub 2011 Sep 18. Lancet Oncol. 2011. PMID: 21933749 Free PMC article.
A phase I/II study of erlotinib in combination with the anti-insulin-like growth factor-1 receptor monoclonal antibody IMC-A12 (cixutumumab) in patients with advanced non-small cell lung cancer.
Weickhardt A, Doebele R, Oton A, Lettieri J, Maxson D, Reynolds M, Brown A, Jackson MK, Dy G, Adjei A, Fetterly G, Lu X, Franklin W, Varella-Garcia M, Hirsch FR, Wynes MW, Youssoufian H, Adjei A, Camidge DR. Weickhardt A, et al. J Thorac Oncol. 2012 Feb;7(2):419-26. doi: 10.1097/JTO.0b013e31823c5b11. J Thorac Oncol. 2012. PMID: 22237261 Free PMC article. Clinical Trial.
157 results