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A meta-analysis of European and Asian cohorts reveals a global role of a functional SNP in the 5' UTR of GDF5 with osteoarthritis susceptibility.
Chapman K, Takahashi A, Meulenbelt I, Watson C, Rodriguez-Lopez J, Egli R, Tsezou A, Malizos KN, Kloppenburg M, Shi D, Southam L, van der Breggen R, Donn R, Qin J, Doherty M, Slagboom PE, Wallis G, Kamatani N, Jiang Q, Gonzalez A, Loughlin J, Ikegawa S. Chapman K, et al. Among authors: doherty m. Hum Mol Genet. 2008 May 15;17(10):1497-504. doi: 10.1093/hmg/ddn038. Epub 2008 Feb 24. Hum Mol Genet. 2008. PMID: 18299287
Genome-wide association scan identifies a prostaglandin-endoperoxide synthase 2 variant involved in risk of knee osteoarthritis.
Valdes AM, Loughlin J, Timms KM, van Meurs JJ, Southam L, Wilson SG, Doherty S, Lories RJ, Luyten FP, Gutin A, Abkevich V, Ge D, Hofman A, Uitterlinden AG, Hart DJ, Zhang F, Zhai G, Egli RJ, Doherty M, Lanchbury J, Spector TD. Valdes AM, et al. Among authors: doherty m, doherty s. Am J Hum Genet. 2008 Jun;82(6):1231-40. doi: 10.1016/j.ajhg.2008.04.006. Epub 2008 May 8. Am J Hum Genet. 2008. PMID: 18471798 Free PMC article.
Large-scale analysis of association between GDF5 and FRZB variants and osteoarthritis of the hip, knee, and hand.
Evangelou E, Chapman K, Meulenbelt I, Karassa FB, Loughlin J, Carr A, Doherty M, Doherty S, Gómez-Reino JJ, Gonzalez A, Halldorsson BV, Hauksson VB, Hofman A, Hart DJ, Ikegawa S, Ingvarsson T, Jiang Q, Jonsdottir I, Jonsson H, Kerkhof HJ, Kloppenburg M, Lane NE, Li J, Lories RJ, van Meurs JB, Näkki A, Nevitt MC, Rodriguez-Lopez J, Shi D, Slagboom PE, Stefansson K, Tsezou A, Wallis GA, Watson CM, Spector TD, Uitterlinden AG, Valdes AM, Ioannidis JP. Evangelou E, et al. Among authors: doherty m, doherty s. Arthritis Rheum. 2009 Jun;60(6):1710-21. doi: 10.1002/art.24524. Arthritis Rheum. 2009. PMID: 19479880 Free PMC article.
Variation at the ANP32A gene is associated with risk of hip osteoarthritis in women.
Valdes AM, Lories RJ, van Meurs JB, Kerkhof H, Doherty S, Hofman A, Hart DJ, Zhang F, Luyten FP, Uitterlinden AG, Doherty M, Spector TD. Valdes AM, et al. Among authors: doherty m, doherty s. Arthritis Rheum. 2009 Jul;60(7):2046-54. doi: 10.1002/art.24627. Arthritis Rheum. 2009. PMID: 19565487 Free article.
A genome-wide association study identifies an osteoarthritis susceptibility locus on chromosome 7q22.
Kerkhof HJ, Lories RJ, Meulenbelt I, Jonsdottir I, Valdes AM, Arp P, Ingvarsson T, Jhamai M, Jonsson H, Stolk L, Thorleifsson G, Zhai G, Zhang F, Zhu Y, van der Breggen R, Carr A, Doherty M, Doherty S, Felson DT, Gonzalez A, Halldorsson BV, Hart DJ, Hauksson VB, Hofman A, Ioannidis JP, Kloppenburg M, Lane NE, Loughlin J, Luyten FP, Nevitt MC, Parimi N, Pols HA, Rivadeneira F, Slagboom EP, Styrkársdóttir U, Tsezou A, van de Putte T, Zmuda J, Spector TD, Stefansson K, Uitterlinden AG, van Meurs JB. Kerkhof HJ, et al. Among authors: doherty m, doherty s. Arthritis Rheum. 2010 Feb;62(2):499-510. doi: 10.1002/art.27184. Arthritis Rheum. 2010. PMID: 20112360 Free PMC article.
1,705 results