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Sequence determination and genetic content of the short unique region in the genome of herpes simplex virus type 1.
McGeoch DJ, Dolan A, Donald S, Rixon FJ. McGeoch DJ, et al. J Mol Biol. 1985 Jan 5;181(1):1-13. doi: 10.1016/0022-2836(85)90320-1. J Mol Biol. 1985. PMID: 2984429
The clones used for most of the analysis gave a short unique length of 12,979 base-pairs. We consider that this region contains 12 genes, which are expressed by mRNAs which have separate promoters, but may share 3'-termination sites, so that all but two mRNAs belong to one …
The clones used for most of the analysis gave a short unique length of 12,979 base-pairs. We consider that this region contains 12 ge …
The genome sequence of herpes simplex virus type 2.
Dolan A, Jamieson FE, Cunningham C, Barnett BC, McGeoch DJ. Dolan A, et al. J Virol. 1998 Mar;72(3):2010-21. doi: 10.1128/JVI.72.3.2010-2021.1998. J Virol. 1998. PMID: 9499055 Free PMC article.
The genomic DNA sequence of herpes simplex virus type 2 (HSV-2) strain HG52 was determined as 154,746 bp with a G+C content of 70.4%. ...A. Dalrymple, A. J. Davison, A. Dolan, M. C. Frame, D. McNab, L. J. Perry, J. E. Scott, and P. Taylor, J. Ge …
The genomic DNA sequence of herpes simplex virus type 2 (HSV-2) strain HG52 was determined as 154,746 bp with a G+C content of 70.4%. …
DNA sequence of the region in the genome of herpes simplex virus type 1 containing the exonuclease gene and neighbouring genes.
McGeoch DJ, Dolan A, Frame MC. McGeoch DJ, et al. Nucleic Acids Res. 1986 Apr 25;14(8):3435-48. doi: 10.1093/nar/14.8.3435. Nucleic Acids Res. 1986. PMID: 3010237 Free PMC article.
We report the sequence of a 7800 base pair region of herpes simplex virus type 1 DNA, representing approximately 0.16 to 0.20 map units in the genome. ...Homologues of five of the genes were found for the distantly related Epstein-Barr virus, with a similar overall …
We report the sequence of a 7800 base pair region of herpes simplex virus type 1 DNA, representing approximately 0.16 to 0.20 map uni …
Sequence analysis of the splice junction in the transcript of herpes simplex virus type 1 gene UL15.
Dolan A, Arbuckle M, McGeoch DJ. Dolan A, et al. Virus Res. 1991 Jun;20(1):97-104. doi: 10.1016/0168-1702(91)90064-3. Virus Res. 1991. PMID: 1656627
We have generated a DNA fragment copied from the transcript across the proposed splice junction by successive use of reverse transcription and the polymerase chain reaction, and have sequenced this fragment to determine the precise structure of the splice junction....
We have generated a DNA fragment copied from the transcript across the proposed splice junction by successive use of reverse transcri …
Complete DNA sequence of the short repeat region in the genome of herpes simplex virus type 1.
McGeoch DJ, Dolan A, Donald S, Brauer DH. McGeoch DJ, et al. Nucleic Acids Res. 1986 Feb 25;14(4):1727-45. doi: 10.1093/nar/14.4.1727. Nucleic Acids Res. 1986. PMID: 3005980 Free PMC article.
The IE175 coding region was identified as a 3894 base sequence of 81.5% G+C DNA. The base composition of this gene is thus the most extreme yet determined, and the IE175 predicted amino acid composition is correspondingly biased, most notably with an alanine content of 20. …
The IE175 coding region was identified as a 3894 base sequence of 81.5% G+C DNA. The base composition of this gene is thus the most e …
The complete DNA sequence of the long unique region in the genome of herpes simplex virus type 1.
McGeoch DJ, Dalrymple MA, Davison AJ, Dolan A, Frame MC, McNab D, Perry LJ, Scott JE, Taylor P. McGeoch DJ, et al. J Gen Virol. 1988 Jul;69 ( Pt 7):1531-74. doi: 10.1099/0022-1317-69-7-1531. J Gen Virol. 1988. PMID: 2839594 Review.
The UL sequence contained 107,943 residues and had a base composition of 66.9% G + C. Together with our previous work, this completes the sequence of HSV-1 DNA, giving a total genome length of 152,260 residues of base composition 68.3% G + C. ...The gene layout for …
The UL sequence contained 107,943 residues and had a base composition of 66.9% G + C. Together with our previous work, this completes …
Structures of herpes simplex virus type 1 genes required for replication of virus DNA.
McGeoch DJ, Dalrymple MA, Dolan A, McNab D, Perry LJ, Taylor P, Challberg MD. McGeoch DJ, et al. J Virol. 1988 Feb;62(2):444-53. doi: 10.1128/JVI.62.2.444-453.1988. J Virol. 1988. PMID: 2826807 Free PMC article.
A. Wu, N. J. Nelson, D. J. McGeoch, and M. D. Challberg, J. Virol. 62:435-443, 1988). Two of the loci represent the well-known genes for DNA polymerase and major DNA-binding protein, but the remainder had little or no previous characterization. ...The sequence of the UL5 p
A. Wu, N. J. Nelson, D. J. McGeoch, and M. D. Challberg, J. Virol. 62:435-443, 1988). Two of the loci represent the well-known genes
Characterization of herpes simplex virus type 2 transcription during latent infection of mouse trigeminal ganglia.
Mitchell WJ, Deshmane SL, Dolan A, McGeoch DJ, Fraser NW. Mitchell WJ, et al. J Virol. 1990 Nov;64(11):5342-8. doi: 10.1128/JVI.64.11.5342-5348.1990. J Virol. 1990. PMID: 2170675 Free PMC article.
Using a cornea trigeminal ganglion model, we have investigated transcription by herpes simplex virus type 2 (HSV-2) during latency in mice. ...A 1.0-kb PvuI-BamHI fragment within the BamHI F fragment and a 0.3-kb BamHI-SalI fragment and a 3.4-kb SalI-B …
Using a cornea trigeminal ganglion model, we have investigated transcription by herpes simplex virus type 2 (HSV-2) during latency in …
Comparative sequence analysis of the long repeat regions and adjoining parts of the long unique regions in the genomes of herpes simplex viruses types 1 and 2.
McGeoch DJ, Cunningham C, McIntyre G, Dolan A. McGeoch DJ, et al. J Gen Virol. 1991 Dec;72 ( Pt 12):3057-75. doi: 10.1099/0022-1317-72-12-3057. J Gen Virol. 1991. PMID: 1662697
Comparison of the HSV-1 and HSV-2 UL56 sequences led to a correction in the published HSV-1 UL56 reading frame. The HSV-2 RL region, including one copy of the a sequence, was determined to be 9263 bp, with a base composition of 75.4% G+C and with many repetit …
Comparison of the HSV-1 and HSV-2 UL56 sequences led to a correction in the published HSV-1 UL56 reading frame. The HSV-2 RL region, …
A novel herpes simplex virus gene (UL49A) encodes a putative membrane protein with counterparts in other herpesviruses.
Barnett BC, Dolan A, Telford EA, Davison AJ, McGeoch DJ. Barnett BC, et al. J Gen Virol. 1992 Aug;73 ( Pt 8):2167-71. doi: 10.1099/0022-1317-73-8-2167. J Gen Virol. 1992. PMID: 1322965
Comparative analysis of DNA sequences located between the coding regions of genes UL49 and UL50 of herpes simplex virus types 1 and 2 (HSV-1 and -2) has revealed a small open reading frame (ORF) of 91 and 87 codons respectively with the characteristics of a genuine …
Comparative analysis of DNA sequences located between the coding regions of genes UL49 and UL50 of herpes simplex virus types 1 and 2 (HSV-1 …
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