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Cyclin D1-Cdk4 controls glucose metabolism independently of cell cycle progression.
Lee Y, Dominy JE, Choi YJ, Jurczak M, Tolliday N, Camporez JP, Chim H, Lim JH, Ruan HB, Yang X, Vazquez F, Sicinski P, Shulman GI, Puigserver P. Lee Y, et al. Among authors: dominy je. Nature. 2014 Jun 26;510(7506):547-51. doi: 10.1038/nature13267. Epub 2014 May 25. Nature. 2014. PMID: 24870244 Free PMC article.
Nuclear FoxO1 inflames insulin resistance.
Dominy JE, Puigserver P. Dominy JE, et al. EMBO J. 2010 Dec 15;29(24):4068-9. doi: 10.1038/emboj.2010.305. EMBO J. 2010. PMID: 21157481 Free PMC article.
The Methionine Transamination Pathway Controls Hepatic Glucose Metabolism through Regulation of the GCN5 Acetyltransferase and the PGC-1α Transcriptional Coactivator.
Tavares CD, Sharabi K, Dominy JE, Lee Y, Isasa M, Orozco JM, Jedrychowski MP, Kamenecka TM, Griffin PR, Gygi SP, Puigserver P. Tavares CD, et al. Among authors: dominy je. J Biol Chem. 2016 May 13;291(20):10635-45. doi: 10.1074/jbc.M115.706200. Epub 2016 Mar 28. J Biol Chem. 2016. PMID: 27022023 Free PMC article.
Selective Chemical Inhibition of PGC-1α Gluconeogenic Activity Ameliorates Type 2 Diabetes.
Sharabi K, Lin H, Tavares CDJ, Dominy JE, Camporez JP, Perry RJ, Schilling R, Rines AK, Lee J, Hickey M, Bennion M, Palmer M, Nag PP, Bittker JA, Perez J, Jedrychowski MP, Ozcan U, Gygi SP, Kamenecka TM, Shulman GI, Schreiber SL, Griffin PR, Puigserver P. Sharabi K, et al. Among authors: dominy je. Cell. 2017 Mar 23;169(1):148-160.e15. doi: 10.1016/j.cell.2017.03.001. Cell. 2017. PMID: 28340340 Free PMC article.
29 results