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Transforming growth factor-beta production and myeloid cells are an effector mechanism through which CD1d-restricted T cells block cytotoxic T lymphocyte-mediated tumor immunosurveillance: abrogation prevents tumor recurrence.
Terabe M, Matsui S, Park JM, Mamura M, Noben-Trauth N, Donaldson DD, Chen W, Wahl SM, Ledbetter S, Pratt B, Letterio JJ, Paul WE, Berzofsky JA. Terabe M, et al. Among authors: donaldson dd. J Exp Med. 2003 Dec 1;198(11):1741-52. doi: 10.1084/jem.20022227. J Exp Med. 2003. PMID: 14657224 Free PMC article.
A push-pull approach to maximize vaccine efficacy: abrogating suppression with an IL-13 inhibitor while augmenting help with granulocyte/macrophage colony-stimulating factor and CD40L.
Ahlers JD, Belyakov IM, Terabe M, Koka R, Donaldson DD, Thomas EK, Berzofsky JA. Ahlers JD, et al. Among authors: donaldson dd. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):13020-5. doi: 10.1073/pnas.192251199. Epub 2002 Sep 13. Proc Natl Acad Sci U S A. 2002. PMID: 12232042 Free PMC article.
IL-13 receptor alpha 2 down-modulates granulomatous inflammation and prolongs host survival in schistosomiasis.
Mentink-Kane MM, Cheever AW, Thompson RW, Hari DM, Kabatereine NB, Vennervald BJ, Ouma JH, Mwatha JK, Jones FM, Donaldson DD, Grusby MJ, Dunne DW, Wynn TA. Mentink-Kane MM, et al. Among authors: donaldson dd. Proc Natl Acad Sci U S A. 2004 Jan 13;101(2):586-90. doi: 10.1073/pnas.0305064101. Epub 2003 Dec 29. Proc Natl Acad Sci U S A. 2004. PMID: 14699044 Free PMC article.
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