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Inhibitors of the hepatitis C virus NS3 protease with basic amine functionality at the P3-amino acid N-terminus: discovery and optimization of a new series of P2-P4 macrocycles.
Harper S, Ferrara M, Crescenzi B, Pompei M, Palumbi MC, DiMuzio JM, Donghi M, Fiore F, Koch U, Liverton NJ, Pesci S, Petrocchi A, Rowley M, Summa V, Gardelli C. Harper S, et al. Among authors: donghi m. J Med Chem. 2009 Aug 13;52(15):4820-37. doi: 10.1021/jm900372w. J Med Chem. 2009. PMID: 19624135
Design and synthesis of bicyclic pyrimidinones as potent and orally bioavailable HIV-1 integrase inhibitors.
Muraglia E, Kinzel O, Gardelli C, Crescenzi B, Donghi M, Ferrara M, Nizi E, Orvieto F, Pescatore G, Laufer R, Gonzalez-Paz O, Di Marco A, Fiore F, Monteagudo E, Fonsi M, Felock PJ, Rowley M, Summa V. Muraglia E, et al. Among authors: donghi m. J Med Chem. 2008 Feb 28;51(4):861-74. doi: 10.1021/jm701164t. Epub 2008 Jan 25. J Med Chem. 2008. PMID: 18217703
Discovery of raltegravir, a potent, selective orally bioavailable HIV-integrase inhibitor for the treatment of HIV-AIDS infection.
Summa V, Petrocchi A, Bonelli F, Crescenzi B, Donghi M, Ferrara M, Fiore F, Gardelli C, Gonzalez Paz O, Hazuda DJ, Jones P, Kinzel O, Laufer R, Monteagudo E, Muraglia E, Nizi E, Orvieto F, Pace P, Pescatore G, Scarpelli R, Stillmock K, Witmer MV, Rowley M. Summa V, et al. Among authors: donghi m. J Med Chem. 2008 Sep 25;51(18):5843-55. doi: 10.1021/jm800245z. J Med Chem. 2008. PMID: 18763751
Phosphoramidate prodrugs of 2'-C-methylcytidine for therapy of hepatitis C virus infection.
Gardelli C, Attenni B, Donghi M, Meppen M, Pacini B, Harper S, Di Marco A, Fiore F, Giuliano C, Pucci V, Laufer R, Gennari N, Marcucci I, Leone JF, Olsen DB, MacCoss M, Rowley M, Narjes F. Gardelli C, et al. Among authors: donghi m. J Med Chem. 2009 Sep 10;52(17):5394-407. doi: 10.1021/jm900447q. J Med Chem. 2009. PMID: 19725579
Structural segregation in GSR from mercuric primers. A preliminary study.
Nunziata F, De Felicis D, Donghi M, Bemporad E, Capone B, Palumbo G, Rotter G. Nunziata F, et al. Among authors: donghi m. Forensic Sci Int. 2024 Feb;355:111931. doi: 10.1016/j.forsciint.2024.111931. Epub 2024 Jan 12. Forensic Sci Int. 2024. PMID: 38232575
27 results