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Genome-wide CRISPR-Cas9 screening reveals ubiquitous T cell cancer targeting via the monomorphic MHC class I-related protein MR1.
Crowther MD, Dolton G, Legut M, Caillaud ME, Lloyd A, Attaf M, Galloway SAE, Rius C, Farrell CP, Szomolay B, Ager A, Parker AL, Fuller A, Donia M, McCluskey J, Rossjohn J, Svane IM, Phillips JD, Sewell AK. Crowther MD, et al. Among authors: Donia M. Nat Immunol. 2020 Feb;21(2):178-185. doi: 10.1038/s41590-019-0578-8. Epub 2020 Jan 20. Nat Immunol. 2020. PMID: 31959982
Induction of caspase-independent apoptotic-like cell death of mouse mammary tumor TA3Ha cells in vitro and reduction of their lethality in vivo by the novel chemotherapeutic agent GIT-27NO.
Mijatovic S, Maksimovic-Ivanic D, Timotijevic G, Miljkovic D, Donia M, Libra M, Coco M, McCubrey J, Al-Abed Y, Korac A, Stosic-Grujicic S, Nicoletti F. Mijatovic S, et al. Among authors: Donia M. Free Radic Biol Med. 2010 Apr 15;48(8):1090-9. doi: 10.1016/j.freeradbiomed.2010.01.026. Epub 2010 Jan 28. Free Radic Biol Med. 2010. PMID: 20114073
Treatment with rapamycin ameliorates clinical and histological signs of protracted relapsing experimental allergic encephalomyelitis in Dark Agouti rats and induces expansion of peripheral CD4+CD25+Foxp3+ regulatory T cells.
Donia M, Mangano K, Amoroso A, Mazzarino MC, Imbesi R, Castrogiovanni P, Coco M, Meroni P, Nicoletti F. Donia M, et al. J Autoimmun. 2009 Sep;33(2):135-40. doi: 10.1016/j.jaut.2009.06.003. Epub 2009 Jul 21. J Autoimmun. 2009. PMID: 19625166
Efficacy of intracolonic administration of low-molecular-weight heparin CB-01-05, compared to other low-molecular-weight heparins and unfractionated heparin, in experimentally induced colitis in rat.
Celasco G, Moro L, Bozzella R, Mangano K, Quattrocchi C, Aiello C, Donia M, Fagone P, Di Marco R. Celasco G, et al. Among authors: Donia M. Dig Dis Sci. 2008 Dec;53(12):3170-5. doi: 10.1007/s10620-008-0299-6. Epub 2008 May 9. Dig Dis Sci. 2008. PMID: 18465235
Novel nitric oxide-donating compound (S,R)-3-phenyl-4,5-dihydro-5-isoxazole acetic acid-nitric oxide (GIT-27NO) induces p53 mediated apoptosis in human A375 melanoma cells.
Mijatovic S, Maksimovic-Ivanic D, Mojic M, Malaponte G, Libra M, Cardile V, Miljkovic D, Harhaji L, Dabideen D, Cheng KF, Bevelacqua Y, Donia M, Garotta G, Al-Abed Y, Stosic-Grujicic S, Nicoletti F. Mijatovic S, et al. Among authors: Donia M. Nitric Oxide. 2008 Sep;19(2):177-83. doi: 10.1016/j.niox.2008.04.004. Epub 2008 May 19. Nitric Oxide. 2008. PMID: 18460348
Unique antineoplastic profile of Saquinavir-NO, a novel NO-derivative of the protease inhibitor Saquinavir, on the in vitro and in vivo tumor formation of A375 human melanoma cells.
Donia M, Mangano K, Fagone P, De Pasquale R, Dinotta F, Coco M, Padron J, Al-Abed Y, Giovanni Lombardo GA, Maksimovic-Ivanic D, Mijatovic S, Zocca MB, Perciavalle V, Stosic-Grujicic S, Nicoletti F. Donia M, et al. Oncol Rep. 2012 Aug;28(2):682-8. doi: 10.3892/or.2012.1840. Epub 2012 May 29. Oncol Rep. 2012. PMID: 22665020
Real-World Impact of Immune Checkpoint Inhibitors in Metastatic Uveal Melanoma.
Bol KF, Ellebaek E, Hoejberg L, Bagger MM, Larsen MS, Klausen TW, Køhler UH, Schmidt H, Bastholt L, Kiilgaard JF, Donia M, Svane IM. Bol KF, et al. Among authors: Donia M. Cancers (Basel). 2019 Oct 3;11(10):1489. doi: 10.3390/cancers11101489. Cancers (Basel). 2019. PMID: 31623302 Free PMC article.
In vitro, ex vivo and in vivo immunopharmacological activities of the isoxazoline compound VGX-1027: modulation of cytokine synthesis and prevention of both organ-specific and systemic autoimmune diseases in murine models.
Stojanovic I, Cuzzocrea S, Mangano K, Mazzon E, Miljkovic D, Wang M, Donia M, Al Abed Y, Kim J, Nicoletti F, Stosic-Grujicic S, Claesson M. Stojanovic I, et al. Among authors: Donia M. Clin Immunol. 2007 Jun;123(3):311-23. doi: 10.1016/j.clim.2007.03.004. Epub 2007 Apr 20. Clin Immunol. 2007. PMID: 17449326
Roles of the Raf/MEK/ERK and PI3K/PTEN/Akt/mTOR pathways in controlling growth and sensitivity to therapy-implications for cancer and aging.
Steelman LS, Chappell WH, Abrams SL, Kempf RC, Long J, Laidler P, Mijatovic S, Maksimovic-Ivanic D, Stivala F, Mazzarino MC, Donia M, Fagone P, Malaponte G, Nicoletti F, Libra M, Milella M, Tafuri A, Bonati A, Bäsecke J, Cocco L, Evangelisti C, Martelli AM, Montalto G, Cervello M, McCubrey JA. Steelman LS, et al. Among authors: Donia M. Aging (Albany NY). 2011 Mar;3(3):192-222. doi: 10.18632/aging.100296. Aging (Albany NY). 2011. PMID: 21422497 Free PMC article. Review.
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