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An approved in vitro approach to preclinical safety and efficacy evaluation of engineered T cell receptor anti-CD3 bispecific (ImmTAC) molecules.
PLoS One. 2018 Oct 15;13(10):e0205491. doi: 10.1371/journal.pone.0205491. eCollection 2018.
PLoS One. 2018.
PMID: 30321203
Free PMC article.
Direct molecular mimicry enables off-target cardiovascular toxicity by an enhanced affinity TCR designed for cancer immunotherapy.
Raman MC, Rizkallah PJ, Simmons R, Donnellan Z, Dukes J, Bossi G, Le Provost GS, Todorov P, Baston E, Hickman E, Mahon T, Hassan N, Vuidepot A, Sami M, Cole DK, Jakobsen BK.
Raman MC, et al. Among authors: donnellan z.
Sci Rep. 2016 Jan 13;6:18851. doi: 10.1038/srep18851.
Sci Rep. 2016.
PMID: 26758806
Free PMC article.
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TCRs with Distinct Specificity Profiles Use Different Binding Modes to Engage an Identical Peptide-HLA Complex.
Coles CH, Mulvaney RM, Malla S, Walker A, Smith KJ, Lloyd A, Lowe KL, McCully ML, Martinez Hague R, Aleksic M, Harper J, Paston SJ, Donnellan Z, Chester F, Wiederhold K, Robinson RA, Knox A, Stacey AR, Dukes J, Baston E, Griffin S, Jakobsen BK, Vuidepot A, Harper S.
Coles CH, et al. Among authors: donnellan z.
J Immunol. 2020 Apr 1;204(7):1943-1953. doi: 10.4049/jimmunol.1900915. Epub 2020 Feb 26.
J Immunol. 2020.
PMID: 32102902
Free PMC article.
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Formation of a Resonance-Stabilized Radical Intermediate by Hydroxyl Radical Addition to Cyclopentadiene.
Caster KL, Lee J, Donnellan Z, Selby TM, Osborn DL, Goulay F.
Caster KL, et al. Among authors: donnellan z.
J Phys Chem A. 2022 Dec 8;126(48):9031-9041. doi: 10.1021/acs.jpca.2c06934. Epub 2022 Nov 23.
J Phys Chem A. 2022.
PMID: 36417297
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Kinetic Investigations of the CH (X2Π) Radical Reaction with Cyclopentadiene.
Caster KL, Donnellan ZN, Selby TM, Goulay F.
Caster KL, et al. Among authors: donnellan zn.
J Phys Chem A. 2019 Jul 11;123(27):5692-5703. doi: 10.1021/acs.jpca.9b03813. Epub 2019 Jun 27.
J Phys Chem A. 2019.
PMID: 31194547
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