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Cyclin B1 and CDK1: nuclear localization and upstream regulators.
Porter LA, Donoghue DJ. Porter LA, et al. Prog Cell Cycle Res. 2003;5:335-47. Prog Cell Cycle Res. 2003. PMID: 14593728 Review.
Receptor Tyrosine Kinases: Translocation Partners in Hematopoietic Disorders.
Nelson KN, Peiris MN, Meyer AN, Siari A, Donoghue DJ. Nelson KN, et al. Trends Mol Med. 2017 Jan;23(1):59-79. doi: 10.1016/j.molmed.2016.11.002. Epub 2016 Dec 14. Trends Mol Med. 2017. PMID: 27988109 Review.
Oncogenic Gene Fusion FGFR3-TACC3 Is Regulated by Tyrosine Phosphorylation.
Nelson KN, Meyer AN, Siari A, Campos AR, Motamedchaboki K, Donoghue DJ. Nelson KN, et al. Mol Cancer Res. 2016 May;14(5):458-69. doi: 10.1158/1541-7786.MCR-15-0497. Epub 2016 Feb 11. Mol Cancer Res. 2016. PMID: 26869289
Initial activation of cyclin-B1-cdc2 kinase requires phosphorylation of cyclin B1.
Peter M, Le Peuch C, Labbé JC, Meyer AN, Donoghue DJ, Dorée M. Peter M, et al. EMBO Rep. 2002 Jun;3(6):551-6. doi: 10.1093/embo-reports/kvf111. Epub 2002 May 24. EMBO Rep. 2002. PMID: 12034754 Free PMC article.
Novel Lys63-linked ubiquitination of IKKβ induces STAT3 signaling.
Gallo LH, Meyer AN, Motamedchaboki K, Nelson KN, Haas M, Donoghue DJ. Gallo LH, et al. Cell Cycle. 2014;13(24):3964-76. doi: 10.4161/15384101.2014.988026. Cell Cycle. 2014. PMID: 25486864 Free PMC article.
KIDs rule: regulatory phosphorylation of RTKs.
Locascio LE, Donoghue DJ. Locascio LE, et al. Trends Biochem Sci. 2013 Feb;38(2):75-84. doi: 10.1016/j.tibs.2012.12.001. Epub 2013 Jan 9. Trends Biochem Sci. 2013. PMID: 23312584 Review.
Nordihydroguaiaretic acid inhibits an activated fibroblast growth factor receptor 3 mutant and blocks downstream signaling in multiple myeloma cells.
Meyer AN, McAndrew CW, Donoghue DJ. Meyer AN, et al. Cancer Res. 2008 Sep 15;68(18):7362-70. doi: 10.1158/0008-5472.CAN-08-0575. Cancer Res. 2008. PMID: 18794123 Free PMC article.
Spy1 enhances phosphorylation and degradation of the cell cycle inhibitor p27.
McAndrew CW, Gastwirt RF, Meyer AN, Porter LA, Donoghue DJ. McAndrew CW, et al. Cell Cycle. 2007 Aug 1;6(15):1937-45. doi: 10.4161/cc.6.15.4520. Epub 2007 May 30. Cell Cycle. 2007. PMID: 17671428
Speedy/RINGO regulation of CDKs in cell cycle, checkpoint activation and apoptosis.
Gastwirt RF, McAndrew CW, Donoghue DJ. Gastwirt RF, et al. Cell Cycle. 2007 May 15;6(10):1188-93. doi: 10.4161/cc.6.10.4252. Epub 2007 May 5. Cell Cycle. 2007. PMID: 17507798 Review.
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