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Positive symptoms associate with cortical thinning in the superior temporal gyrus via the ENIGMA Schizophrenia consortium.
Walton E, Hibar DP, van Erp TG, Potkin SG, Roiz-Santiañez R, Crespo-Facorro B, Suarez-Pinilla P, Van Haren NE, de Zwarte SM, Kahn RS, Cahn W, Doan NT, Jørgensen KN, Gurholt TP, Agartz I, Andreassen OA, Westlye LT, Melle I, Berg AO, Mørch-Johnsen L, Faerden A, Flyckt L, Fatouros-Bergman H; Karolinska Schizophrenia Project Consortium (KaSP), Jönsson EG, Hashimoto R, Yamamori H, Fukunaga M, Preda A, De Rossi P, Piras F, Banaj N, Ciullo V, Spalletta G, Gur RE, Gur RC, Wolf DH, Satterthwaite TD, Beard LM, Sommer IE, Koops S, Gruber O, Richter A, Krämer B, Kelly S, Donohoe G, McDonald C, Cannon DM, Corvin A, Gill M, Di Giorgio A, Bertolino A, Lawrie S, Nickson T, Whalley HC, Neilson E, Calhoun VD, Thompson PM, Turner JA, Ehrlich S. Walton E, et al. Among authors: Donohoe G. Acta Psychiatr Scand. 2017 May;135(5):439-447. doi: 10.1111/acps.12718. Epub 2017 Mar 29. Acta Psychiatr Scand. 2017. PMID: 28369804 Free PMC article. Clinical Trial.
Can specific deficits in executive functioning explain the negative symptoms of schizophrenia? A review.
Donohoe G, Robertson IH. Donohoe G, et al. Neurocase. 2003 Apr;9(2):97-108. doi: 10.1076/neur.9.2.97.15075. Neurocase. 2003. PMID: 12925934 Review.
Difficulties with traditional clinical measures (e.g. the Wisconsin Card Sorting Test; WCST) in separating these processes are highlighted. ...
Difficulties with traditional clinical measures (e.g. the Wisconsin Card Sorting Test; WCST) in separating these processes are highli …
Chitinase-3-like 1 (CHI3L1) gene and schizophrenia: genetic association and a potential functional mechanism.
Yang MS, Morris DW, Donohoe G, Kenny E, O'Dushalaine CT, Schwaiger S, Nangle JM, Clarke S, Scully P, Quinn J, Meagher D, Baldwin P, Crumlish N, O'Callaghan E, Waddington JL, Gill M, Corvin A. Yang MS, et al. Among authors: Donohoe G. Biol Psychiatry. 2008 Jul 15;64(2):98-103. doi: 10.1016/j.biopsych.2007.12.012. Epub 2008 Feb 20. Biol Psychiatry. 2008. PMID: 18281018
Reduced occipital and prefrontal brain volumes in dysbindin-associated schizophrenia.
Donohoe G, Frodl T, Morris D, Spoletini I, Cannon DM, Cherubini A, Caltagirone C, Bossù P, McDonald C, Gill M, Corvin AP, Spalletta G. Donohoe G, et al. Neuropsychopharmacology. 2010 Jan;35(2):368-73. doi: 10.1038/npp.2009.140. Neuropsychopharmacology. 2010. PMID: 19794403 Free PMC article.
Replicated genetic evidence supports a role for HOMER2 in schizophrenia.
Gilks WP, Allott EH, Donohoe G, Cummings E; International Schizophrenia Consortium, Gill M, Corvin AP, Morris DW. Gilks WP, et al. Among authors: Donohoe G. Neurosci Lett. 2010 Jan 14;468(3):229-33. doi: 10.1016/j.neulet.2009.11.003. Epub 2009 Nov 13. Neurosci Lett. 2010. PMID: 19914345
Childhood stress, serotonin transporter gene and brain structures in major depression.
Frodl T, Reinhold E, Koutsouleris N, Donohoe G, Bondy B, Reiser M, Möller HJ, Meisenzahl EM. Frodl T, et al. Among authors: Donohoe G. Neuropsychopharmacology. 2010 May;35(6):1383-90. doi: 10.1038/npp.2010.8. Epub 2010 Feb 10. Neuropsychopharmacology. 2010. PMID: 20147891 Free PMC article.
The NOS1 variant rs6490121 is associated with variation in prefrontal function and grey matter density in healthy individuals.
Rose EJ, Greene C, Kelly S, Morris DW, Robertson IH, Fahey C, Jacobson S, O'Doherty J, Newell FN, McGrath J, Bokde A, Garavan H, Frodl T, Gill M, Corvin AP, Donohoe G. Rose EJ, et al. Among authors: Donohoe G. Neuroimage. 2012 Mar;60(1):614-22. doi: 10.1016/j.neuroimage.2011.12.054. Epub 2011 Dec 29. Neuroimage. 2012. PMID: 22227051
In healthy individuals (N=157), voxel based morphometry was used to compare grey matter (GM) volume between homozygous and heterozygous carriers of the 'G' allele (i.e. the allele associated with impaired cognition and schizophrenia risk) and homozygous carriers of the non-risk 'A' allele. ...An a priori region-of-interest analysis identified a significant reduction in ventromedial prefrontal GM volume in 'G' allele carriers. ...
In healthy individuals (N=157), voxel based morphometry was used to compare grey matter (GM) volume between homozygous and heterozygous carr …
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