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The roots of bioinformatics in protein evolution.
Doolittle RF. Doolittle RF. PLoS Comput Biol. 2010 Jul 29;6(7):e1000875. doi: 10.1371/journal.pcbi.1000875. PLoS Comput Biol. 2010. PMID: 20686682 Free PMC article. Review. No abstract available.
Step-by-step evolution of vertebrate blood coagulation.
Doolittle RF. Doolittle RF. Cold Spring Harb Symp Quant Biol. 2009;74:35-40. doi: 10.1101/sqb.2009.74.001. Epub 2009 Aug 10. Cold Spring Harb Symp Quant Biol. 2009. PMID: 19667012 Review.
Evolution of the contact phase of vertebrate blood coagulation.
Ponczek MB, Gailani D, Doolittle RF. Ponczek MB, et al. Among authors: doolittle rf. J Thromb Haemost. 2008 Nov;6(11):1876-83. doi: 10.1111/j.1538-7836.2008.03143.x. Epub 2008 Aug 28. J Thromb Haemost. 2008. PMID: 18761718 Free PMC article.
Correlating structure and function during the evolution of fibrinogen-related domains.
Doolittle RF, McNamara K, Lin K. Doolittle RF, et al. Protein Sci. 2012 Dec;21(12):1808-23. doi: 10.1002/pro.2177. Protein Sci. 2012. PMID: 23076991 Free PMC article. Review.
Two families of synthetic peptides that enhance fibrin turbidity and delay fibrinolysis by different mechanisms.
Pandi L, Kollman JM, Lopez-Lira F, Burrows JM, Riley M, Doolittle RF. Pandi L, et al. Among authors: doolittle rf. Biochemistry. 2009 Aug 4;48(30):7201-8. doi: 10.1021/bi900647g. Biochemistry. 2009. PMID: 19588915
Differences in binding specificity for the homologous gamma- and beta-chain "holes" on fibrinogen: exclusive binding of Ala-His-Arg-Pro-amide by the beta-chain hole.
Doolittle RF, Chen A, Pandi L. Doolittle RF, et al. Biochemistry. 2006 Nov 28;45(47):13962-9. doi: 10.1021/bi061219e. Biochemistry. 2006. PMID: 17115691
Natively unfolded regions of the vertebrate fibrinogen molecule.
Doolittle RF, Kollman JM. Doolittle RF, et al. Proteins. 2006 May 1;63(2):391-7. doi: 10.1002/prot.20758. Proteins. 2006. PMID: 16288455 Review.
The evolution of vertebrate blood coagulation as viewed from a comparison of puffer fish and sea squirt genomes.
Jiang Y, Doolittle RF. Jiang Y, et al. Among authors: doolittle rf. Proc Natl Acad Sci U S A. 2003 Jun 24;100(13):7527-32. doi: 10.1073/pnas.0932632100. Epub 2003 Jun 13. Proc Natl Acad Sci U S A. 2003. PMID: 12808152 Free PMC article.
Bacterial actins? An evolutionary perspective.
Doolittle RF, York AL. Doolittle RF, et al. Bioessays. 2002 Apr;24(4):293-6. doi: 10.1002/bies.10079. Bioessays. 2002. PMID: 11948613 Review.
Bioinformatic Characterization of Genes and Proteins Involved in Blood Clotting in Lampreys.
Doolittle RF. Doolittle RF. J Mol Evol. 2015 Oct;81(3-4):121-30. doi: 10.1007/s00239-015-9701-0. Epub 2015 Oct 5. J Mol Evol. 2015. PMID: 26437661 Free article.
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