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The 5' flanking region of the human bone morphogenetic protein-7 gene.
Dorai H, Shepard A, Ozkaynak E, Lin K, Jones S, Oppermann H, Sampath K. Dorai H, et al. Biochem Biophys Res Commun. 2001 Apr 6;282(3):823-31. doi: 10.1006/bbrc.2001.4645. Biochem Biophys Res Commun. 2001. PMID: 11401538
Osteogenic protein-1 (bone morphogenetic protein-7) reduces severity of injury after ischemic acute renal failure in rat.
Vukicevic S, Basic V, Rogic D, Basic N, Shih MS, Shepard A, Jin D, Dattatreyamurty B, Jones W, Dorai H, Ryan S, Griffiths D, Maliakal J, Jelic M, Pastorcic M, Stavljenic A, Sampath TK. Vukicevic S, et al. J Clin Invest. 1998 Jul 1;102(1):202-14. doi: 10.1172/JCI2237. J Clin Invest. 1998. PMID: 9649574 Free PMC article.
We show that OP-1 preserves kidney function, as determined by reduced blood urea nitrogen and serum creatinine, and increased survival rate when administered 10 min before or 1 or 16 h after ischemia, and then at 24-h intervals up to 72 h after reperfusion. . …
We show that OP-1 preserves kidney function, as determined by reduced blood urea nitrogen and serum creatinine, and increased survival rate …
Bone morphogenetic protein-7 (osteogenic protein-1) inhibits smooth muscle cell proliferation and stimulates the expression of markers that are characteristic of SMC phenotype in vitro.
Dorai H, Vukicevic S, Sampath TK. Dorai H, et al. J Cell Physiol. 2000 Jul;184(1):37-45. doi: 10.1002/(SICI)1097-4652(200007)184:1<37::AID-JCP4>3.0.CO;2-M. J Cell Physiol. 2000. PMID: 10825232
We report here that bone morphogenetic protein-7 (BMP-7), a member of the transforming growth factor-beta (TGF-beta) superfamily, is capable of inhibiting both serum-stimulated and growth factor-induced (platelet-derived growth factor [PDGF-BB] and TGF-beta1) cell growth as measu …
We report here that bone morphogenetic protein-7 (BMP-7), a member of the transforming growth factor-beta (TGF-beta) superfamily, is capable …
Genome-wide analysis of mouse myeloma cell lines expressing therapeutic antibodies.
Dorai H, Li K, Huang CC, Bittner A, Galindo J, Carmen A. Dorai H, et al. Biotechnol Prog. 2007 Jul-Aug;23(4):911-20. doi: 10.1021/bp0700051. Epub 2007 Jun 26. Biotechnol Prog. 2007. PMID: 17592857
Combining high-throughput screening of caspase activity with anti-apoptosis genes for development of robust CHO production cell lines.
Dorai H, Ellis D, Keung YS, Campbell M, Zhuang M, Lin C, Betenbaugh MJ. Dorai H, et al. Biotechnol Prog. 2010 Sep-Oct;26(5):1367-81. doi: 10.1002/btpr.426. Biotechnol Prog. 2010. PMID: 20945491
Mammalian cell expression of single-chain Fv (sFv) antibody proteins and their C-terminal fusions with interleukin-2 and other effector domains.
Dorai H, McCartney JE, Hudziak RM, Tai MS, Laminet AA, Houston LL, Huston JS, Oppermann H. Dorai H, et al. Biotechnology (N Y). 1994 Sep;12(9):890-7. doi: 10.1038/nbt0994-890. Biotechnology (N Y). 1994. PMID: 7765352
Development of mammalian production cell lines expressing CNTO736, a glucagon like peptide-1-MIMETIBODY: factors that influence productivity and product quality.
Dorai H, Nemeth JF, Cammaart E, Wang Y, Tang QM, Magill A, Lewis MJ, Raju TS, Picha K, O'Neil K, Ganguly S, Moore G. Dorai H, et al. Biotechnol Bioeng. 2009 May 1;103(1):162-76. doi: 10.1002/bit.22217. Biotechnol Bioeng. 2009. PMID: 19137588
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