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B-Raf and C-Raf are required for melanocyte stem cell self-maintenance.
Valluet A, Druillennec S, Barbotin C, Dorard C, Monsoro-Burq AH, Larcher M, Pouponnot C, Baccarini M, Larue L, Eychène A. Valluet A, et al. Among authors: dorard c. Cell Rep. 2012 Oct 25;2(4):774-80. doi: 10.1016/j.celrep.2012.08.020. Epub 2012 Sep 27. Cell Rep. 2012. PMID: 23022482 Free article.
Deciphering the RAS/ERK pathway in vivo.
Dorard C, Vucak G, Baccarini M. Dorard C, et al. Biochem Soc Trans. 2017 Feb 8;45(1):27-36. doi: 10.1042/BST20160135. Biochem Soc Trans. 2017. PMID: 28202657 Review.
Expression of a mutant HSP110 sensitizes colorectal cancer cells to chemotherapy and improves disease prognosis.
Dorard C, de Thonel A, Collura A, Marisa L, Svrcek M, Lagrange A, Jego G, Wanherdrick K, Joly AL, Buhard O, Gobbo J, Penard-Lacronique V, Zouali H, Tubacher E, Kirzin S, Selves J, Milano G, Etienne-Grimaldi MC, Bengrine-Lefèvre L, Louvet C, Tournigand C, Lefèvre JH, Parc Y, Tiret E, Fléjou JF, Gaub MP, Garrido C, Duval A. Dorard C, et al. Nat Med. 2011 Sep 25;17(10):1283-9. doi: 10.1038/nm.2457. Nat Med. 2011. PMID: 21946539
Patients with colorectal tumors with microsatellite instability and large deletions in HSP110 T17 have improved response to 5-fluorouracil–based chemotherapy.
Collura A, Lagrange A, Svrcek M, Marisa L, Buhard O, Guilloux A, Wanherdrick K, Dorard C, Taieb A, Saget A, Loh M, Soong R, Zeps N, Platell C, Mews A, Iacopetta B, De Thonel A, Seigneuric R, Marcion G, Chapusot C, Lepage C, Bouvier AM, Gaub MP, Milano G, Selves J, Senet P, Delarue P, Arzouk H, Lacoste C, Coquelle A, Bengrine-Lefèvre L, Tournigand C, Lefèvre JH, Parc Y, Biard DS, Fléjou JF, Garrido C, Duval A. Collura A, et al. Among authors: dorard c. Gastroenterology. 2014 Feb;146(2):401-11.e1. doi: 10.1053/j.gastro.2013.10.054. Gastroenterology. 2014. PMID: 24512910
HSP110 T17 simplifies and improves the microsatellite instability testing in patients with colorectal cancer.
Buhard O, Lagrange A, Guilloux A, Colas C, Chouchène M, Wanherdrick K, Coulet F, Guillerm E, Dorard C, Marisa L, Bokhari A, Greene M, El-Murr N, Bodo S, Muleris M, Sourouille I, Svrcek M, Cervera P, Blanché H, Lefevre JH, Parc Y, Lepage C, Chapusot C, Bouvier AM, Gaub MP, Selves J, Garrett K, Iacopetta B, Soong R, Hamelin R, Garrido C, Lascols O, André T, Fléjou JF, Collura A, Duval A. Buhard O, et al. Among authors: dorard c. J Med Genet. 2016 Jun;53(6):377-84. doi: 10.1136/jmedgenet-2015-103518. Epub 2016 Feb 1. J Med Genet. 2016. PMID: 26831756
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