Skip to main page content
Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Text availability
Article attribute
Article type
Publication date

Search Results

73 results
Filters applied: . Clear all Results are displayed in a computed author sort order. Results by year timeline is unavailable
Page 1
Impact of inter-individual differences in drug metabolism and pharmacokinetics on safety evaluation.
Dorne JL. Dorne JL. Fundam Clin Pharmacol. 2004 Dec;18(6):609-20. doi: 10.1111/j.1472-8206.2004.00292.x. Fundam Clin Pharmacol. 2004. PMID: 15548231 Review.
Human and environmental risk assessment of pharmaceuticals: differences, similarities, lessons from toxicology.
Dorne JL, Skinner L, Frampton GK, Spurgeon DJ, Ragas AM. Dorne JL, et al. Anal Bioanal Chem. 2007 Feb;387(4):1259-68. doi: 10.1007/s00216-006-0963-7. Epub 2006 Dec 22. Anal Bioanal Chem. 2007. PMID: 17186225 Review.
Trends in human risk assessment of pharmaceuticals.
Dorne JL, Ragas AM, Frampton GK, Spurgeon DS, Lewis DF. Dorne JL, et al. Anal Bioanal Chem. 2007 Feb;387(4):1167-72. doi: 10.1007/s00216-006-0961-9. Epub 2007 Jan 5. Anal Bioanal Chem. 2007. PMID: 17205262 No abstract available.
Metabolism, variability and risk assessment.
Dorne JL. Dorne JL. Toxicology. 2010 Feb 9;268(3):156-64. doi: 10.1016/j.tox.2009.11.004. Epub 2009 Nov 20. Toxicology. 2010. PMID: 19932147 Review.
Human variability in hepatic and renal elimination: implications for risk assessment.
Dorne JL. Dorne JL. J Appl Toxicol. 2007 Sep-Oct;27(5):411-20. doi: 10.1002/jat.1255. J Appl Toxicol. 2007. PMID: 17497760 Review.
The refinement of uncertainty/safety factors in risk assessment by the incorporation of data on toxicokinetic variability in humans.
Dorne JL, Renwick AG. Dorne JL, et al. Toxicol Sci. 2005 Jul;86(1):20-6. doi: 10.1093/toxsci/kfi160. Epub 2005 Mar 30. Toxicol Sci. 2005. PMID: 15800035
Human variability in xenobiotic metabolism and pathway-related uncertainty factors for chemical risk assessment: a review.
Dorne JL, Walton K, Renwick AG. Dorne JL, et al. Food Chem Toxicol. 2005 Feb;43(2):203-16. doi: 10.1016/j.fct.2004.05.011. Food Chem Toxicol. 2005. PMID: 15621332 Review.
Human variability for metabolic pathways with limited data (CYP2A6, CYP2C9, CYP2E1, ADH, esterases, glycine and sulphate conjugation).
Dorne JL, Walton K, Renwick AG. Dorne JL, et al. Food Chem Toxicol. 2004 Mar;42(3):397-421. doi: 10.1016/j.fct.2003.10.003. Food Chem Toxicol. 2004. PMID: 14871582
Human variability in the renal elimination of foreign compounds and renal excretion-related uncertainty factors for risk assessment.
Dorne JL, Walton K, Renwick AG. Dorne JL, et al. Food Chem Toxicol. 2004 Feb;42(2):275-98. doi: 10.1016/j.fct.2003.09.002. Food Chem Toxicol. 2004. PMID: 14667473 Review.
Species-specific uncertainty factors for compounds eliminated principally by renal excretion in humans.
Walton K, Dorne JL, Renwick AG. Walton K, et al. Among authors: dorne jl. Food Chem Toxicol. 2004 Feb;42(2):261-74. doi: 10.1016/j.fct.2003.09.001. Food Chem Toxicol. 2004. PMID: 14667472 Review.
73 results
Jump to page
Feedback