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18F9 (4-(3,6-bis (ethoxycarbonyl)-4,5,6,7-tetrahydrothieno (2,3-c) pyridin-2-ylamino)-4-oxobutanoic acid) enhances insulin-mediated glucose uptake in vitro and exhibits antidiabetic activity in vivo in db/db mice.
Anandharajan R, Sayyed SG, Doshi LS, Dixit P, Chandak PG, Dixit AV, Brahma MK, Deshmukh NJ, Gupte R, Damre A, Suthar J, Padigaru M, Sharma SD, Nemmani KV. Anandharajan R, et al. Among authors: doshi ls. Metabolism. 2009 Oct;58(10):1503-16. doi: 10.1016/j.metabol.2009.04.036. Epub 2009 Jul 15. Metabolism. 2009. PMID: 19608207 Free article.
Isocytosine-based inhibitors of xanthine oxidase: design, synthesis, SAR, PK and in vivo efficacy in rat model of hyperuricemia.
Khanna S, Burudkar S, Bajaj K, Shah P, Keche A, Ghosh U, Desai A, Srivastava A, Kulkarni-Almeida A, Deshmukh NJ, Dixit A, Brahma MK, Bahirat U, Doshi L, Nemmani KV, Tannu P, Damre A, B-Rao C, Sharma R, Sivaramakrishnan H. Khanna S, et al. Bioorg Med Chem Lett. 2012 Dec 15;22(24):7543-6. doi: 10.1016/j.bmcl.2012.10.029. Epub 2012 Oct 13. Bioorg Med Chem Lett. 2012. PMID: 23122864
Exploration of pyridine containing heteroaryl analogs of biaryl ureas as DGAT1 inhibitors.
Motiwala H, Kandre S, Birar V, Kadam KS, Rodge A, Jadhav RD, Mahesh Kumar Reddy M, Brahma MK, Deshmukh NJ, Dixit A, Doshi L, Gupte A, Gangopadhyay AK, Vishwakarma RA, Srinivasan S, Sharma M, Nemmani KV, Sharma R. Motiwala H, et al. Bioorg Med Chem Lett. 2011 Oct 1;21(19):5812-7. doi: 10.1016/j.bmcl.2011.07.109. Epub 2011 Aug 4. Bioorg Med Chem Lett. 2011. PMID: 21868220
Synthesis and biological evaluation of isoxazole, oxazole, and oxadiazole containing heteroaryl analogs of biaryl ureas as DGAT1 inhibitors.
Jadhav RD, Kadam KS, Kandre S, Guha T, Reddy MM, Brahma MK, Deshmukh NJ, Dixit A, Doshi L, Potdar N, Enose AA, Vishwakarma RA, Sivaramakrishnan H, Srinivasan S, Nemmani KV, Gupte A, Gangopadhyay AK, Sharma R. Jadhav RD, et al. Eur J Med Chem. 2012 Aug;54:324-42. doi: 10.1016/j.ejmech.2012.05.016. Epub 2012 May 22. Eur J Med Chem. 2012. PMID: 22683241
Fermentation, Isolation, Structure, and antidiabetic activity of NFAT-133 produced by Streptomyces strain PM0324667.
Kulkarni-Almeida AA, Brahma MK, Padmanabhan P, Mishra PD, Parab RR, Gaikwad NV, Thakkar CS, Tokdar P, Ranadive PV, Nair AS, Damre AA, Bahirat UA, Deshmukh NJ, Doshi LS, Dixit AV, George SD, Vishwakarma RA, Nemmani KV, Mahajan GB. Kulkarni-Almeida AA, et al. Among authors: doshi ls. AMB Express. 2011 Nov 21;1(1):42. doi: 10.1186/2191-0855-1-42. AMB Express. 2011. PMID: 22104600 Free PMC article.
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