Functional Assays to Screen and Dissect Genomic Hits: Doubling Down on the National Investment in Genomic Research.
Circ Genom Precis Med. 2018.
PMID: 29654098
Free PMC article.
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Functional Assays to Screen and Dissect Genomic Hits: Doubling Down on the National Investment in Genomic Research.
Musunuru K, Bernstein D, Cole FS, Khokha MK, Lee FS, Lin S, McDonald TV, Moskowitz IP, Quertermous T, Sankaran VG, Schwartz DA, Silverman EK, Zhou X, Hasan AAK, Luo XJ.
Musunuru K, et al.
Circ Genom Precis Med. 2018 Apr;11(4):e002178. doi: 10.1161/CIRCGEN.118.002178.
Circ Genom Precis Med. 2018.
PMID: 29654098
Free PMC article.
Review.
The National Institutes of Health have made substantial investments in genomic studies and technologies to identify DNA sequence variants associated with human disease phenotypes. ...We discuss priorities that can accelerate the impressive but incomplete prog …
The National Institutes of Health have made substantial investments in genomic studies and technologies to identify DNA …
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Downregulation of c-Myc is involved in TLR3-mediated tumor death of neuroblastoma xenografts.
Lin LL, Huang CC, Wu CL, Wu MT, Hsu WM, Chuang JH.
Lin LL, et al.
Lab Invest. 2016 Jul;96(7):719-30. doi: 10.1038/labinvest.2016.57. Epub 2016 May 16.
Lab Invest. 2016.
PMID: 27183205
Free article.
In the innate immune system, toll-like receptor 3 (TLR3) recognizes viral double-stranded RNAs to initiate immune signaling. Positive TLR3 expression indicates a favorable prognosis in NB patients, and is associated with MYCN-non-amplified. ...
In the innate immune system, toll-like receptor 3 (TLR3) recognizes viral double-stranded RNAs to initiate immune signaling. Positive …
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