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A multisubunit ribozyme that is a catalyst of and template for complementary strand RNA synthesis.
Doudna JA, Couture S, Szostak JW. Doudna JA, et al. Science. 1991 Mar 29;251(5001):1605-8. doi: 10.1126/science.1707185. Science. 1991. PMID: 1707185
Mutational analysis of conserved nucleotides in a self-splicing group I intron.
Couture S, Ellington AD, Gerber AS, Cherry JM, Doudna JA, Green R, Hanna M, Pace U, Rajagopal J, Szostak JW. Couture S, et al. Among authors: doudna ja. J Mol Biol. 1990 Oct 5;215(3):345-58. doi: 10.1016/s0022-2836(05)80356-0. J Mol Biol. 1990. PMID: 1700131
Specificity for aminoacylation of an RNA helix: an unpaired, exocyclic amino group in the minor groove.
Musier-Forsyth K, Usman N, Scaringe S, Doudna J, Green R, Schimmel P. Musier-Forsyth K, et al. Among authors: doudna j. Science. 1991 Aug 16;253(5021):784-6. doi: 10.1126/science.1876835. Science. 1991. PMID: 1876835
Template-directed primer extension catalyzed by the Tetrahymena ribozyme.
Bartel DP, Doudna JA, Usman N, Szostak JW. Bartel DP, et al. Among authors: doudna ja. Mol Cell Biol. 1991 Jun;11(6):3390-4. doi: 10.1128/mcb.11.6.3390. Mol Cell Biol. 1991. PMID: 2038341 Free PMC article.
Genetic dissection of an RNA enzyme.
Doudna JA, Gerber AS, Cherry JM, Szostak JW. Doudna JA, et al. Cold Spring Harb Symp Quant Biol. 1987;52:173-80. doi: 10.1101/sqb.1987.052.01.022. Cold Spring Harb Symp Quant Biol. 1987. PMID: 2456876 No abstract available.
Stereochemical course of catalysis by the Tetrahymena ribozyme.
Rajagopal J, Doudna JA, Szostak JW. Rajagopal J, et al. Among authors: doudna ja. Science. 1989 May 12;244(4905):692-4. doi: 10.1126/science.2470151. Science. 1989. PMID: 2470151
RNA-catalysed synthesis of complementary-strand RNA.
Doudna JA, Szostak JW. Doudna JA, et al. Nature. 1989 Jun 15;339(6225):519-22. doi: 10.1038/339519a0. Nature. 1989. PMID: 2660003
RNA structure, not sequence, determines the 5' splice-site specificity of a group I intron.
Doudna JA, Cormack BP, Szostak JW. Doudna JA, et al. Proc Natl Acad Sci U S A. 1989 Oct;86(19):7402-6. doi: 10.1073/pnas.86.19.7402. Proc Natl Acad Sci U S A. 1989. PMID: 2678103 Free PMC article.
Miniribozymes, small derivatives of the sunY intron, are catalytically active.
Doudna JA, Szostak JW. Doudna JA, et al. Mol Cell Biol. 1989 Dec;9(12):5480-3. doi: 10.1128/mcb.9.12.5480. Mol Cell Biol. 1989. PMID: 2685567 Free PMC article.
Self-assembly of a group I intron active site from its component tertiary structural domains.
Doudna JA, Cech TR. Doudna JA, et al. RNA. 1995 Mar;1(1):36-45. RNA. 1995. PMID: 7489486 Free PMC article.
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