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Conformational control of DNA target cleavage by CRISPR-Cas9.
Sternberg SH, LaFrance B, Kaplan M, Doudna JA. Sternberg SH, et al. Among authors: doudna ja. Nature. 2015 Nov 5;527(7576):110-3. doi: 10.1038/nature15544. Epub 2015 Oct 28. Nature. 2015. PMID: 26524520 Free PMC article.
Ribozyme catalysis: not different, just worse.
Doudna JA, Lorsch JR. Doudna JA, et al. Nat Struct Mol Biol. 2005 May;12(5):395-402. doi: 10.1038/nsmb932. Nat Struct Mol Biol. 2005. PMID: 15870731 Review.
Substrate-specific kinetics of Dicer-catalyzed RNA processing.
Chakravarthy S, Sternberg SH, Kellenberger CA, Doudna JA. Chakravarthy S, et al. Among authors: doudna ja. J Mol Biol. 2010 Dec 3;404(3):392-402. doi: 10.1016/j.jmb.2010.09.030. Epub 2010 Oct 13. J Mol Biol. 2010. PMID: 20932845 Free PMC article.
Structural basis for CRISPR RNA-guided DNA recognition by Cascade.
Jore MM, Lundgren M, van Duijn E, Bultema JB, Westra ER, Waghmare SP, Wiedenheft B, Pul U, Wurm R, Wagner R, Beijer MR, Barendregt A, Zhou K, Snijders AP, Dickman MJ, Doudna JA, Boekema EJ, Heck AJ, van der Oost J, Brouns SJ. Jore MM, et al. Among authors: doudna ja. Nat Struct Mol Biol. 2011 May;18(5):529-36. doi: 10.1038/nsmb.2019. Epub 2011 Apr 3. Nat Struct Mol Biol. 2011. PMID: 21460843
381 results