Doudna JA - Search Results

1

High-throughput biochemical profiling reveals sequence determinants of dCas9 off-target binding and unbinding.

Boyle EA, Andreasson JOL, Chircus LM, Sternberg SH, Wu MJ, Guegler CK, Doudna JA, Greenleaf WJ. Boyle EA, et al. Among authors: doudna ja. Proc Natl Acad Sci U S A. 2017 May 23;114(21):5461-5466. doi: 10.1073/pnas.1700557114. Epub 2017 May 11. Proc Natl Acad Sci U S A. 2017. PMID: 28495970 Free PMC article.

2

Specificity of RNA-RNA helix recognition.

Battle DJ, Doudna JA. Battle DJ, et al. Among authors: doudna ja. Proc Natl Acad Sci U S A. 2002 Sep 3;99(18):11676-81. doi: 10.1073/pnas.182221799. Epub 2002 Aug 20. Proc Natl Acad Sci U S A. 2002. PMID: 12189204 Free PMC article.

3

Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA.

Ji H, Fraser CS, Yu Y, Leary J, Doudna JA. Ji H, et al. Among authors: doudna ja. Proc Natl Acad Sci U S A. 2004 Dec 7;101(49):16990-5. doi: 10.1073/pnas.0407402101. Epub 2004 Nov 24. Proc Natl Acad Sci U S A. 2004. PMID: 15563596 Free PMC article.

4

Substrate-specific kinetics of Dicer-catalyzed RNA processing.

Chakravarthy S, Sternberg SH, Kellenberger CA, Doudna JA. Chakravarthy S, et al. Among authors: doudna ja. J Mol Biol. 2010 Dec 3;404(3):392-402. doi: 10.1016/j.jmb.2010.09.030. Epub 2010 Oct 13. J Mol Biol. 2010. PMID: 20932845 Free PMC article.

5

RNA-guided complex from a bacterial immune system enhances target recognition through seed sequence interactions.

Wiedenheft B, van Duijn E, Bultema JB, Waghmare SP, Zhou K, Barendregt A, Westphal W, Heck AJ, Boekema EJ, Dickman MJ, Doudna JA. Wiedenheft B, et al. Among authors: doudna ja. Proc Natl Acad Sci U S A. 2011 Jun 21;108(25):10092-7. doi: 10.1073/pnas.1102716108. Epub 2011 May 2. Proc Natl Acad Sci U S A. 2011. PMID: 21536913 Free PMC article.

6

Multiplexed RNA structure characterization with selective 2'-hydroxyl acylation analyzed by primer extension sequencing (SHAPE-Seq).

Lucks JB, Mortimer SA, Trapnell C, Luo S, Aviran S, Schroth GP, Pachter L, Doudna JA, Arkin AP. Lucks JB, et al. Among authors: doudna ja. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11063-8. doi: 10.1073/pnas.1106501108. Epub 2011 Jun 3. Proc Natl Acad Sci U S A. 2011. PMID: 21642531 Free PMC article.

7

Modeling and automation of sequencing-based characterization of RNA structure.

Aviran S, Trapnell C, Lucks JB, Mortimer SA, Luo S, Schroth GP, Doudna JA, Arkin AP, Pachter L. Aviran S, et al. Among authors: doudna ja. Proc Natl Acad Sci U S A. 2011 Jul 5;108(27):11069-74. doi: 10.1073/pnas.1106541108. Epub 2011 Jun 3. Proc Natl Acad Sci U S A. 2011. PMID: 21642536 Free PMC article.

8

RNA-guided genetic silencing systems in bacteria and archaea.

Wiedenheft B, Sternberg SH, Doudna JA. Wiedenheft B, et al. Among authors: doudna ja. Nature. 2012 Feb 15;482(7385):331-8. doi: 10.1038/nature10886. Nature. 2012. PMID: 22337052 Review.

9

Mechanism of substrate selection by a highly specific CRISPR endoribonuclease.

Sternberg SH, Haurwitz RE, Doudna JA. Sternberg SH, et al. Among authors: doudna ja. RNA. 2012 Apr;18(4):661-72. doi: 10.1261/rna.030882.111. Epub 2012 Feb 16. RNA. 2012. PMID: 22345129 Free PMC article.

10

Csy4 relies on an unusual catalytic dyad to position and cleave CRISPR RNA.

Haurwitz RE, Sternberg SH, Doudna JA. Haurwitz RE, et al. Among authors: doudna ja. EMBO J. 2012 Jun 13;31(12):2824-32. doi: 10.1038/emboj.2012.107. Epub 2012 Apr 20. EMBO J. 2012. PMID: 22522703 Free PMC article.

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