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Microbial translocation across the GI tract.
Brenchley JM, Douek DC. Brenchley JM, et al. Annu Rev Immunol. 2012;30:149-73. doi: 10.1146/annurev-immunol-020711-075001. Epub 2012 Jan 3. Annu Rev Immunol. 2012. PMID: 22224779 Free PMC article. Review.
Nonprogressive and progressive primate immunodeficiency lentivirus infections.
Brenchley JM, Silvestri G, Douek DC. Brenchley JM, et al. Immunity. 2010 Jun 25;32(6):737-42. doi: 10.1016/j.immuni.2010.06.004. Immunity. 2010. PMID: 20620940 Free PMC article. Review.
The Interplay Between Host Genetic Variation, Viral Replication, and Microbial Translocation in Untreated HIV-Infected Individuals.
Perkins MR, Bartha I, Timmer JK, Liebner JC, Wolinsky D, G√ľnthard HF, Hauser C, Bernasconi E, Hoffmann M, Calmy A, Battegay M, Telenti A, Douek DC, Fellay J; Swiss HIV Cohort Study. Perkins MR, et al. J Infect Dis. 2015 Aug 15;212(4):578-84. doi: 10.1093/infdis/jiv089. Epub 2015 Feb 20. J Infect Dis. 2015. PMID: 25701868 Free PMC article.
Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections.
Estes JD, Harris LD, Klatt NR, Tabb B, Pittaluga S, Paiardini M, Barclay GR, Smedley J, Pung R, Oliveira KM, Hirsch VM, Silvestri G, Douek DC, Miller CJ, Haase AT, Lifson J, Brenchley JM. Estes JD, et al. PLoS Pathog. 2010 Aug 19;6(8):e1001052. doi: 10.1371/journal.ppat.1001052. PLoS Pathog. 2010. PMID: 20808901 Free PMC article.
Emerging concepts in the immunopathogenesis of AIDS.
Douek DC, Roederer M, Koup RA. Douek DC, et al. Annu Rev Med. 2009;60:471-84. doi: 10.1146/annurev.med.60.041807.123549. Annu Rev Med. 2009. PMID: 18947296 Free PMC article. Review.
Host response to translocated microbial products predicts outcomes of patients with HBV or HCV infection.
Sandler NG, Koh C, Roque A, Eccleston JL, Siegel RB, Demino M, Kleiner DE, Deeks SG, Liang TJ, Heller T, Douek DC. Sandler NG, et al. Gastroenterology. 2011 Oct;141(4):1220-30, 1230.e1-3. doi: 10.1053/j.gastro.2011.06.063. Epub 2011 Jul 2. Gastroenterology. 2011. PMID: 21726511 Free PMC article.
The mucosal barrier and immune activation in HIV pathogenesis.
Brenchley JM, Douek DC. Brenchley JM, et al. Curr Opin HIV AIDS. 2008 May;3(3):356-61. doi: 10.1097/COH.0b013e3282f9ae9c. Curr Opin HIV AIDS. 2008. PMID: 19372990 Free PMC article.
Microbial translocation is a cause of systemic immune activation in chronic HIV infection.
Brenchley JM, Price DA, Schacker TW, Asher TE, Silvestri G, Rao S, Kazzaz Z, Bornstein E, Lambotte O, Altmann D, Blazar BR, Rodriguez B, Teixeira-Johnson L, Landay A, Martin JN, Hecht FM, Picker LJ, Lederman MM, Deeks SG, Douek DC. Brenchley JM, et al. Nat Med. 2006 Dec;12(12):1365-71. doi: 10.1038/nm1511. Epub 2006 Nov 19. Nat Med. 2006. PMID: 17115046
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