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Immune therapy for cancer.
Dougan M, Dranoff G. Dougan M, et al. Annu Rev Immunol. 2009;27:83-117. doi: 10.1146/annurev.immunol.021908.132544. Annu Rev Immunol. 2009. PMID: 19007331 Review.
MFG-E8-mediated uptake of apoptotic cells by APCs links the pro- and antiinflammatory activities of GM-CSF.
Jinushi M, Nakazaki Y, Dougan M, Carrasco DR, Mihm M, Dranoff G. Jinushi M, et al. Among authors: dougan m. J Clin Invest. 2007 Jul;117(7):1902-13. doi: 10.1172/JCI30966. J Clin Invest. 2007. PMID: 17557120 Free PMC article.
Inciting inflammation: the RAGE about tumor promotion.
Dougan M, Dranoff G. Dougan M, et al. J Exp Med. 2008 Feb 18;205(2):267-70. doi: 10.1084/jem.20080136. Epub 2008 Feb 11. J Exp Med. 2008. PMID: 18268042 Free PMC article.
The immune response to tumors.
Dougan M, Dranoff G. Dougan M, et al. Curr Protoc Immunol. 2009 Apr;Chapter 20:Unit 20.11. doi: 10.1002/0471142735.im2011s85. Curr Protoc Immunol. 2009. PMID: 19347848
IAP inhibitors enhance co-stimulation to promote tumor immunity.
Dougan M, Dougan S, Slisz J, Firestone B, Vanneman M, Draganov D, Goyal G, Li W, Neuberg D, Blumberg R, Hacohen N, Porter D, Zawel L, Dranoff G. Dougan M, et al. Among authors: dougan s. J Exp Med. 2010 Sep 27;207(10):2195-206. doi: 10.1084/jem.20101123. Epub 2010 Sep 13. J Exp Med. 2010. PMID: 20837698 Free PMC article.
A dual role for the immune response in a mouse model of inflammation-associated lung cancer.
Dougan M, Li D, Neuberg D, Mihm M, Googe P, Wong KK, Dranoff G. Dougan M, et al. J Clin Invest. 2011 Jun;121(6):2436-46. doi: 10.1172/JCI44796. Epub 2011 May 2. J Clin Invest. 2011. PMID: 21537082 Free PMC article.
Transnuclear TRP1-specific CD8 T cells with high or low affinity TCRs show equivalent antitumor activity.
Dougan SK, Dougan M, Kim J, Turner JA, Ogata S, Cho HI, Jaenisch R, Celis E, Ploegh HL. Dougan SK, et al. Among authors: dougan m. Cancer Immunol Res. 2013 Aug;1(2):99-111. doi: 10.1158/2326-6066.CIR-13-0047. Cancer Immunol Res. 2013. PMID: 24459675 Free PMC article.
Durable antitumor responses to CD47 blockade require adaptive immune stimulation.
Sockolosky JT, Dougan M, Ingram JR, Ho CC, Kauke MJ, Almo SC, Ploegh HL, Garcia KC. Sockolosky JT, et al. Among authors: dougan m. Proc Natl Acad Sci U S A. 2016 May 10;113(19):E2646-54. doi: 10.1073/pnas.1604268113. Epub 2016 Apr 18. Proc Natl Acad Sci U S A. 2016. PMID: 27091975 Free PMC article.
Clinical Dosing Regimen of Selinexor Maintains Normal Immune Homeostasis and T-cell Effector Function in Mice: Implications for Combination with Immunotherapy.
Tyler PM, Servos MM, de Vries RC, Klebanov B, Kashyap T, Sacham S, Landesman Y, Dougan M, Dougan SK. Tyler PM, et al. Among authors: dougan sk, dougan m. Mol Cancer Ther. 2017 Mar;16(3):428-439. doi: 10.1158/1535-7163.MCT-16-0496. Epub 2017 Feb 1. Mol Cancer Ther. 2017. PMID: 28148714 Free PMC article.
Targeting Immunotherapy to the Tumor Microenvironment.
Dougan M, Dougan SK. Dougan M, et al. Among authors: dougan sk. J Cell Biochem. 2017 Oct;118(10):3049-3054. doi: 10.1002/jcb.26005. Epub 2017 May 15. J Cell Biochem. 2017. PMID: 28332219 Review.
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