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Neural and developmental actions of lithium: a unifying hypothesis.
Berridge MJ, Downes CP, Hanley MR. Berridge MJ, et al. Among authors: downes cp. Cell. 1989 Nov 3;59(3):411-9. doi: 10.1016/0092-8674(89)90026-3. Cell. 1989. PMID: 2553271 Review. No abstract available.
The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins.
Harrington LS, Findlay GM, Gray A, Tolkacheva T, Wigfield S, Rebholz H, Barnett J, Leslie NR, Cheng S, Shepherd PR, Gout I, Downes CP, Lamb RF. Harrington LS, et al. Among authors: downes cp. J Cell Biol. 2004 Jul 19;166(2):213-23. doi: 10.1083/jcb.200403069. Epub 2004 Jul 12. J Cell Biol. 2004. PMID: 15249583 Free PMC article.
Disruption by lithium of phosphoinositide signalling in cerebellar granule cells in primary culture.
del Río E, Shinomura T, van der Kaay J, Nicholls DG, Downes CP. del Río E, et al. Among authors: downes cp. J Neurochem. 1998 Apr;70(4):1662-9. doi: 10.1046/j.1471-4159.1998.70041662.x. J Neurochem. 1998. PMID: 9523584
Receptor-stimulated inositol phospholipid metabolism in the central nervous system.
Downes CP. Downes CP. Cell Calcium. 1982 Oct;3(4-5):413-28. doi: 10.1016/0143-4160(82)90027-6. Cell Calcium. 1982. PMID: 6130848 Review. No abstract available.
Characterization of the effects of lithium and inositol on phosphoinositide turnover in cerebellar granule cells in primary culture.
del Río E, Nicholls DG, Downes CP. del Río E, et al. Among authors: downes cp. J Neurochem. 1996 Feb;66(2):517-24. doi: 10.1046/j.1471-4159.1996.66020517.x. J Neurochem. 1996. PMID: 8592121
Beta1-integrin and PTEN control the phosphorylation of protein kinase C.
Parekh DB, Katso RM, Leslie NR, Downes CP, Procyk KJ, Waterfield MD, Parker PJ. Parekh DB, et al. Among authors: downes cp. Biochem J. 2000 Dec 1;352 Pt 2(Pt 2):425-33. Biochem J. 2000. PMID: 11085936 Free PMC article.
The role of dynamin and its binding partners in coated pit invagination and scission.
Hill E, van Der Kaay J, Downes CP, Smythe E. Hill E, et al. Among authors: downes cp. J Cell Biol. 2001 Jan 22;152(2):309-23. doi: 10.1083/jcb.152.2.309. J Cell Biol. 2001. PMID: 11266448 Free PMC article.
MyosinV controls PTEN function and neuronal cell size.
van Diepen MT, Parsons M, Downes CP, Leslie NR, Hindges R, Eickholt BJ. van Diepen MT, et al. Among authors: downes cp. Nat Cell Biol. 2009 Oct;11(10):1191-6. doi: 10.1038/ncb1961. Epub 2009 Sep 20. Nat Cell Biol. 2009. PMID: 19767745 Free PMC article.
dS6K-regulated cell growth is dPKB/dPI(3)K-independent, but requires dPDK1.
Radimerski T, Montagne J, Rintelen F, Stocker H, van der Kaay J, Downes CP, Hafen E, Thomas G. Radimerski T, et al. Among authors: downes cp. Nat Cell Biol. 2002 Mar;4(3):251-5. doi: 10.1038/ncb763. Nat Cell Biol. 2002. PMID: 11862217
Substrate specificity and acute regulation of the tumour suppressor phosphatase, PTEN.
Downes CP, Perera N, Ross S, Leslie NR. Downes CP, et al. Biochem Soc Symp. 2007;(74):69-80. doi: 10.1042/BSS0740069. Biochem Soc Symp. 2007. PMID: 17233581 Review.
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