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Humanized xenobiotic response in mice expressing nuclear receptor SXR.
Xie W, Barwick JL, Downes M, Blumberg B, Simon CM, Nelson MC, Neuschwander-Tetri BA, Brunt EM, Guzelian PS, Evans RM. Xie W, et al. Among authors: downes m. Nature. 2000 Jul 27;406(6794):435-9. doi: 10.1038/35019116. Nature. 2000. PMID: 10935643
Pregnane X receptor prevents hepatorenal toxicity from cholesterol metabolites.
Sonoda J, Chong LW, Downes M, Barish GD, Coulter S, Liddle C, Lee CH, Evans RM. Sonoda J, et al. Among authors: downes m. Proc Natl Acad Sci U S A. 2005 Feb 8;102(6):2198-203. doi: 10.1073/pnas.0409481102. Epub 2005 Jan 25. Proc Natl Acad Sci U S A. 2005. PMID: 15671183 Free PMC article.
A Nuclear Receptor Atlas: 3T3-L1 adipogenesis.
Fu M, Sun T, Bookout AL, Downes M, Yu RT, Evans RM, Mangelsdorf DJ. Fu M, et al. Among authors: downes m. Mol Endocrinol. 2005 Oct;19(10):2437-50. doi: 10.1210/me.2004-0539. Epub 2005 Jul 28. Mol Endocrinol. 2005. PMID: 16051663
A Nuclear Receptor Atlas: macrophage activation.
Barish GD, Downes M, Alaynick WA, Yu RT, Ocampo CB, Bookout AL, Mangelsdorf DJ, Evans RM. Barish GD, et al. Among authors: downes m. Mol Endocrinol. 2005 Oct;19(10):2466-77. doi: 10.1210/me.2004-0529. Epub 2005 Jul 28. Mol Endocrinol. 2005. PMID: 16051664
Benefit of farnesoid X receptor inhibition in obstructive cholestasis.
Stedman C, Liddle C, Coulter S, Sonoda J, Alvarez JG, Evans RM, Downes M. Stedman C, et al. Among authors: downes m. Proc Natl Acad Sci U S A. 2006 Jul 25;103(30):11323-8. doi: 10.1073/pnas.0604772103. Epub 2006 Jul 14. Proc Natl Acad Sci U S A. 2006. PMID: 16844773 Free PMC article.
495 results