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340 results
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Acute myeloid leukemia.
Löwenberg B, Downing JR, Burnett A. Löwenberg B, et al. Among authors: downing jr. N Engl J Med. 1999 Sep 30;341(14):1051-62. doi: 10.1056/NEJM199909303411407. N Engl J Med. 1999. PMID: 10502596 Review. No abstract available.
Pediatric non-Down syndrome acute megakaryoblastic leukemia is characterized by distinct genomic subsets with varying outcomes.
de Rooij JD, Branstetter C, Ma J, Li Y, Walsh MP, Cheng J, Obulkasim A, Dang J, Easton J, Verboon LJ, Mulder HL, Zimmermann M, Koss C, Gupta P, Edmonson M, Rusch M, Lim JY, Reinhardt K, Pigazzi M, Song G, Yeoh AE, Shih LY, Liang DC, Halene S, Krause DS, Zhang J, Downing JR, Locatelli F, Reinhardt D, van den Heuvel-Eibrink MM, Zwaan CM, Fornerod M, Gruber TA. de Rooij JD, et al. Among authors: downing jr. Nat Genet. 2017 Mar;49(3):451-456. doi: 10.1038/ng.3772. Epub 2017 Jan 23. Nat Genet. 2017. PMID: 28112737 Free PMC article.
The genetic basis and cell of origin of mixed phenotype acute leukaemia.
Alexander TB, Gu Z, Iacobucci I, Dickerson K, Choi JK, Xu B, Payne-Turner D, Yoshihara H, Loh ML, Horan J, Buldini B, Basso G, Elitzur S, de Haas V, Zwaan CM, Yeoh A, Reinhardt D, Tomizawa D, Kiyokawa N, Lammens T, De Moerloose B, Catchpoole D, Hori H, Moorman A, Moore AS, Hrusak O, Meshinchi S, Orgel E, Devidas M, Borowitz M, Wood B, Heerema NA, Carrol A, Yang YL, Smith MA, Davidsen TM, Hermida LC, Gesuwan P, Marra MA, Ma Y, Mungall AJ, Moore RA, Jones SJM, Valentine M, Janke LJ, Rubnitz JE, Pui CH, Ding L, Liu Y, Zhang J, Nichols KE, Downing JR, Cao X, Shi L, Pounds S, Newman S, Pei D, Guidry Auvil JM, Gerhard DS, Hunger SP, Inaba H, Mullighan CG. Alexander TB, et al. Among authors: downing jr. Nature. 2018 Oct;562(7727):373-379. doi: 10.1038/s41586-018-0436-0. Epub 2018 Sep 12. Nature. 2018. PMID: 30209392 Free PMC article.
Treating childhood acute lymphoblastic leukemia without cranial irradiation.
Pui CH, Campana D, Pei D, Bowman WP, Sandlund JT, Kaste SC, Ribeiro RC, Rubnitz JE, Raimondi SC, Onciu M, Coustan-Smith E, Kun LE, Jeha S, Cheng C, Howard SC, Simmons V, Bayles A, Metzger ML, Boyett JM, Leung W, Handgretinger R, Downing JR, Evans WE, Relling MV. Pui CH, et al. Among authors: downing jr. N Engl J Med. 2009 Jun 25;360(26):2730-41. doi: 10.1056/NEJMoa0900386. N Engl J Med. 2009. PMID: 19553647 Free PMC article. Clinical Trial.
Acute lymphoblastic leukemia.
Pui CH, Relling MV, Downing JR. Pui CH, et al. Among authors: downing jr. N Engl J Med. 2004 Apr 8;350(15):1535-48. doi: 10.1056/NEJMra023001. N Engl J Med. 2004. PMID: 15071128 Review. No abstract available.
Acute leukemia: a pediatric perspective.
Downing JR, Shannon KM. Downing JR, et al. Cancer Cell. 2002 Dec;2(6):437-45. doi: 10.1016/s1535-6108(02)00211-8. Cancer Cell. 2002. PMID: 12498712 Review.
Expression of the outcome predictor in acute leukemia 1 (OPAL1) gene is not an independent prognostic factor in patients treated according to COALL or St Jude protocols.
Holleman A, den Boer ML, Cheok MH, Kazemier KM, Pei D, Downing JR, Janka-Schaub GE, Göbel U, Graubner UB, Pui CH, Evans WE, Pieters R. Holleman A, et al. Among authors: downing jr. Blood. 2006 Sep 15;108(6):1984-90. doi: 10.1182/blood-2006-04-015990. Epub 2006 May 18. Blood. 2006. PMID: 16709928 Free PMC article. Clinical Trial.
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