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Prodromal dysfunction of α5GABA-A receptor modulated hippocampal ripples occurs prior to neurodegeneration in the TgF344-AD rat model of Alzheimer's disease.
Heliyon. 2021 Sep 1;7(9):e07895. doi: 10.1016/j.heliyon.2021.e07895. eCollection 2021 Sep.
Heliyon. 2021.
PMID: 34568591
Free PMC article.
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Benzodiazepine modulation of partial agonist efficacy and spontaneously active GABA(A) receptors supports an allosteric model of modulation.
Downing SS, Lee YT, Farb DH, Gibbs TT.
Downing SS, et al.
Br J Pharmacol. 2005 Aug;145(7):894-906. doi: 10.1038/sj.bjp.0706251.
Br J Pharmacol. 2005.
PMID: 15912137
Free PMC article.
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Pharmacological Properties of DOV 315,090, an ocinaplon metabolite.
Berezhnoy D, Gravielle MC, Downing S, Kostakis E, Basile AS, Skolnick P, Gibbs TT, Farb DH.
Berezhnoy D, et al.
BMC Pharmacol. 2008 Jun 13;8:11. doi: 10.1186/1471-2210-8-11.
BMC Pharmacol. 2008.
PMID: 18554397
Free PMC article.
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"I Remember Feeling Pretty Darn Lucky": Crafting Family Resilience in Response to a Medical Emergency.
Downing SS.
Downing SS.
Health Commun. 2023 Dec 19:1-10. doi: 10.1080/10410236.2023.2296187. Online ahead of print.
Health Commun. 2023.
PMID: 38115225
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Systematic analysis of cell cycle effects of common drugs leads to the discovery of a suppressive interaction between gemfibrozil and fluoxetine.
Hoose SA, Duran C, Malik I, Eslamfam S, Shasserre SC, Downing SS, Hoover EM, Dowd KE, Smith R 3rd, Polymenis M.
Hoose SA, et al. Among authors: downing ss.
PLoS One. 2012;7(5):e36503. doi: 10.1371/journal.pone.0036503. Epub 2012 May 2.
PLoS One. 2012.
PMID: 22567160
Free PMC article.
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A systematic analysis of cell cycle regulators in yeast reveals that most factors act independently of cell size to control initiation of division.
Hoose SA, Rawlings JA, Kelly MM, Leitch MC, Ababneh QO, Robles JP, Taylor D, Hoover EM, Hailu B, McEnery KA, Downing SS, Kaushal D, Chen Y, Rife A, Brahmbhatt KA, Smith R 3rd, Polymenis M.
Hoose SA, et al. Among authors: downing ss.
PLoS Genet. 2012;8(3):e1002590. doi: 10.1371/journal.pgen.1002590. Epub 2012 Mar 15.
PLoS Genet. 2012.
PMID: 22438835
Free PMC article.
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