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Mechanoresponsive stem cells to target cancer metastases through biophysical cues.
Liu L, Zhang SX, Liao W, Farhoodi HP, Wong CW, Chen CC, Ségaliny AI, Chacko JV, Nguyen LP, Lu M, Polovin G, Pone EJ, Downing TL, Lawson DA, Digman MA, Zhao W. Liu L, et al. Among authors: downing tl. Sci Transl Med. 2017 Jul 26;9(400):eaan2966. doi: 10.1126/scitranslmed.aan2966. Sci Transl Med. 2017. PMID: 28747514 Free PMC article.
Biophysical regulation of macrophages in health and disease.
Meli VS, Veerasubramanian PK, Atcha H, Reitz Z, Downing TL, Liu WF. Meli VS, et al. Among authors: downing tl. J Leukoc Biol. 2019 Aug;106(2):283-299. doi: 10.1002/JLB.MR0318-126R. Epub 2019 Mar 12. J Leukoc Biol. 2019. PMID: 30861205 Free PMC article. Review.
YAP-mediated mechanotransduction tunes the macrophage inflammatory response.
Meli VS, Atcha H, Veerasubramanian PK, Nagalla RR, Luu TU, Chen EY, Guerrero-Juarez CF, Yamaga K, Pandori W, Hsieh JY, Downing TL, Fruman DA, Lodoen MB, Plikus MV, Wang W, Liu WF. Meli VS, et al. Among authors: downing tl. Sci Adv. 2020 Dec 4;6(49):eabb8471. doi: 10.1126/sciadv.abb8471. Print 2020 Dec. Sci Adv. 2020. PMID: 33277245 Free PMC article.
Biophysical regulation of epigenetic state and cell reprogramming.
Downing TL, Soto J, Morez C, Houssin T, Fritz A, Yuan F, Chu J, Patel S, Schaffer DV, Li S. Downing TL, et al. Nat Mater. 2013 Dec;12(12):1154-62. doi: 10.1038/nmat3777. Epub 2013 Oct 20. Nat Mater. 2013. PMID: 24141451 Free PMC article.
23 results