Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 6
1981 2
1982 9
1983 12
1984 12
1985 22
1986 20
1987 23
1988 15
1989 16
1990 23
1991 16
1992 17
1993 29
1994 23
1995 26
1996 23
1997 24
1998 35
1999 41
2000 39
2001 42
2002 37
2003 36
2004 39
2005 38
2006 35
2007 19
2008 19
2009 14
2010 16
2011 18
2012 16
2013 15
2014 9
2015 7
2016 8
2017 5
2018 4
2019 3
2020 6
2021 6
2022 3
2023 3
2024 0

Text availability

Article attribute

Article type

Publication date

Search Results

804 results

Results by year

Filters applied: . Clear all
Page 1
Doxifluridine in advanced colorectal cancer.
Calabresi F, Repetto M. Calabresi F, et al. J Surg Oncol Suppl. 1991;2:124-8. doi: 10.1002/jso.2930480526. J Surg Oncol Suppl. 1991. PMID: 1832539 Review. No abstract available.
Doxifluridine-based pharmacosomes delivering miR-122 as tumor microenvironments-activated nanoplatforms for synergistic treatment of hepatocellular carcinoma.
Xue F, Lin X, Cai Z, Liu X, Ma Y, Wu M. Xue F, et al. Colloids Surf B Biointerfaces. 2021 Jan;197:111367. doi: 10.1016/j.colsurfb.2020.111367. Epub 2020 Sep 23. Colloids Surf B Biointerfaces. 2021. PMID: 33007506
A novel kind of anti-cancer pharmacosome (named NPC-D) derived from Doxifluridine (5'-DFUR) was described, which could be activated by tumor microenvironments (TMEs). ...
A novel kind of anti-cancer pharmacosome (named NPC-D) derived from Doxifluridine (5'-DFUR) was described, which could be activated b …
Doxifluridine versus Tegafur/Gimeracil/Oteracil (S-1) as adjuvant chemotherapy for patients with gastric cancer after gastrectomy: A propensity score-matched analysis.
Jeong JY, Seo SH, Kim KH, An MS, Baik H, Kang SH, Oh SH. Jeong JY, et al. Asian J Surg. 2023 Sep;46(9):3656-3662. doi: 10.1016/j.asjsur.2023.03.065. Epub 2023 Mar 29. Asian J Surg. 2023. PMID: 37002050 Free article.
INTRODUCTION: Doxifluridine (DF), an oral 5-FU prodrug, has been used for various solid cancers due to its efficacy and low toxicity. ...
INTRODUCTION: Doxifluridine (DF), an oral 5-FU prodrug, has been used for various solid cancers due to its efficacy and low toxicity. …
Doxifluridine-conjugated 2-5A analog shows strong RNase L activation ability and tumor suppressive effect.
Kitamura Y, Kito S, Nakashima R, Tanaka K, Nagaoka K, Kitade Y. Kitamura Y, et al. Bioorg Med Chem. 2016 Aug 15;24(16):3870-4. doi: 10.1016/j.bmc.2016.06.033. Epub 2016 Jun 16. Bioorg Med Chem. 2016. PMID: 27364610
In this study, we synthesized various 5'-modified 2-5A analogs with 8-methyladenosine at the 2'-terminus. The doxifluridine-conjugated 8-methyladenosine-substituted 2-5A analog was significantly more effective as an activator of RNase L than the parent 5'-monophophorylated …
In this study, we synthesized various 5'-modified 2-5A analogs with 8-methyladenosine at the 2'-terminus. The doxifluridine-conjugate …
Survival benefits of adjuvant chemotherapy with oral doxifluridine (5'-DFUR) following radiotherapy in patients with unresectable pancreatic cancer.
Tsuruta K, Okamoto A, Egawa N, Kamisawa T, Karasawa K, Takahashi T. Tsuruta K, et al. J Surg Oncol. 2001 Nov;78(3):202-7. doi: 10.1002/jso.1151. J Surg Oncol. 2001. PMID: 11745808 Review.
We assessed the survival benefits of oral adjuvant chemotherapy with doxifluridine (5'-DFUR) following radiotherapy for patients with the disease. ...
We assessed the survival benefits of oral adjuvant chemotherapy with doxifluridine (5'-DFUR) following radiotherapy for patients with …
Metronomic doxifluridine chemotherapy combined with the anti-angiogenic agent TNP-470 inhibits the growth of human uterine carcinosarcoma xenografts.
Naganuma Y, Choijamts B, Shirota K, Nakajima K, Ogata S, Miyamoto S, Kawarabayashi T, Emoto M. Naganuma Y, et al. Cancer Sci. 2011 Aug;102(8):1545-52. doi: 10.1111/j.1349-7006.2011.01998.x. Epub 2011 Jul 3. Cancer Sci. 2011. PMID: 21631643 Free article.
The antitumor and anti-angiogenic effects of metronomic doxifluridine (delivered via oral gavage) in combination with TNP-470 were evaluated in vivo. ...Metronomic doxifluridine alone significantly suppressed tumor growth compared with the untreated (control) group, …
The antitumor and anti-angiogenic effects of metronomic doxifluridine (delivered via oral gavage) in combination with TNP-470 were ev …
Subconjunctival doxifluridine administration suppresses rat choroidal neovascularization through activated thymidine phosphorylase.
Yanagi Y, Tamaki Y, Inoue Y, Obata R, Muranaka K, Homma N. Yanagi Y, et al. Invest Ophthalmol Vis Sci. 2003 Feb;44(2):751-4. doi: 10.1167/iovs.02-0222. Invest Ophthalmol Vis Sci. 2003. PMID: 12556409
Previous studies have demonstrated that TP is upregulated in the lesions where pathologic angiogenesis occurs and TP itself promotes angiogenesis. To investigate the possible role of TP and doxifluridine in choroidal neovascularization (CNV), the expression level of TP was …
Previous studies have demonstrated that TP is upregulated in the lesions where pathologic angiogenesis occurs and TP itself promotes angioge …
Pharmacokinetic analysis of doxifluridine and its metabolites, 5-fluorouracil and 5-fluorouridine, after oral administration in beagle dogs.
Baek IH, Lee BY, Kim MS, Kwon KI. Baek IH, et al. Eur J Drug Metab Pharmacokinet. 2013 Dec;38(4):295-9. doi: 10.1007/s13318-013-0130-4. Epub 2013 Apr 7. Eur J Drug Metab Pharmacokinet. 2013. PMID: 23564503
The purpose of this study was to investigate the pharmacokinetic properties of doxifluridine and its two major metabolites, 5-FU, and 5-fluorouridine (5-FUrd), in beagle dogs following a single oral administration of 200 mg doxifluridine capsule (Furtulon()). ...The …
The purpose of this study was to investigate the pharmacokinetic properties of doxifluridine and its two major metabolites, 5-FU, and …
804 results