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Phosphorylation and activation of human cdc25-C by cdc2--cyclin B and its involvement in the self-amplification of MPF at mitosis.
Hoffmann I, Clarke PR, Marcote MJ, Karsenti E, Draetta G. Hoffmann I, et al. Among authors: draetta g. EMBO J. 1993 Jan;12(1):53-63. EMBO J. 1993. PMID: 8428594 Free PMC article.
Cdc25A phosphatase: combinatorial phosphorylation, ubiquitylation and proteolysis.
Busino L, Chiesa M, Draetta GF, Donzelli M. Busino L, et al. Among authors: draetta gf. Oncogene. 2004 Mar 15;23(11):2050-6. doi: 10.1038/sj.onc.1207394. Oncogene. 2004. PMID: 15021892 Review.
Degradation of Cdc25A by beta-TrCP during S phase and in response to DNA damage.
Busino L, Donzelli M, Chiesa M, Guardavaccaro D, Ganoth D, Dorrello NV, Hershko A, Pagano M, Draetta GF. Busino L, et al. Among authors: draetta gf. Nature. 2003 Nov 6;426(6962):87-91. doi: 10.1038/nature02082. Nature. 2003. PMID: 14603323
Regulating mammalian checkpoints through Cdc25 inactivation.
Donzelli M, Draetta GF. Donzelli M, et al. Among authors: draetta gf. EMBO Rep. 2003 Jul;4(7):671-7. doi: 10.1038/sj.embor.embor887. EMBO Rep. 2003. PMID: 12835754 Free PMC article. Review.
The adenovirus protein Gam1 interferes with sumoylation of histone deacetylase 1.
Colombo R, Boggio R, Seiser C, Draetta GF, Chiocca S. Colombo R, et al. Among authors: draetta gf. EMBO Rep. 2002 Nov;3(11):1062-8. doi: 10.1093/embo-reports/kvf213. Epub 2002 Oct 22. EMBO Rep. 2002. PMID: 12393750 Free PMC article.
Dual mode of degradation of Cdc25 A phosphatase.
Donzelli M, Squatrito M, Ganoth D, Hershko A, Pagano M, Draetta GF. Donzelli M, et al. Among authors: draetta gf. EMBO J. 2002 Sep 16;21(18):4875-84. doi: 10.1093/emboj/cdf491. EMBO J. 2002. PMID: 12234927 Free PMC article.
We found that Cdc25 A degradation during mitotic exit and in early G(1) is mediated by the anaphase-promoting complex or cyclosome (APC/C)(Cdh1) ligase, and that a KEN-box motif in the N-terminus of the protein is required for its targeted degradation. ...
We found that Cdc25 A degradation during mitotic exit and in early G(1) is mediated by the anaphase-promoting complex or cyclosome (A …
UBPY: a growth-regulated human ubiquitin isopeptidase.
Naviglio S, Mattecucci C, Matoskova B, Nagase T, Nomura N, Di Fiore PP, Draetta GF. Naviglio S, et al. Among authors: draetta gf. EMBO J. 1998 Jun 15;17(12):3241-50. doi: 10.1093/emboj/17.12.3241. EMBO J. 1998. PMID: 9628861 Free PMC article.
Human Cdc25 A inactivation in response to S phase inhibition and its role in preventing premature mitosis.
Molinari M, Mercurio C, Dominguez J, Goubin F, Draetta GF. Molinari M, et al. Among authors: draetta gf. EMBO Rep. 2000 Jul;1(1):71-9. doi: 10.1093/embo-reports/kvd018. EMBO Rep. 2000. PMID: 11256629 Free PMC article.
p27 cytoplasmic localization is regulated by phosphorylation on Ser10 and is not a prerequisite for its proteolysis.
Rodier G, Montagnoli A, Di Marcotullio L, Coulombe P, Draetta GF, Pagano M, Meloche S. Rodier G, et al. Among authors: draetta gf. EMBO J. 2001 Dec 3;20(23):6672-82. doi: 10.1093/emboj/20.23.6672. EMBO J. 2001. PMID: 11726503 Free PMC article.
Cdc25 protein phosphatases in cell proliferation.
Draetta G, Eckstein J. Draetta G, et al. Biochim Biophys Acta. 1997 Apr 18;1332(2):M53-63. doi: 10.1016/s0304-419x(96)00049-2. Biochim Biophys Acta. 1997. PMID: 9141461 Review. No abstract available.
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