Dragatsis I - Search Results

1

Time course of early motor and neuropathological anomalies in a knock-in mouse model of Huntington's disease with 140 CAG repeats.

Menalled LB, Sison JD, Dragatsis I, Zeitlin S, Chesselet MF. Menalled LB, et al. Among authors: dragatsis i. J Comp Neurol. 2003 Oct 6;465(1):11-26. doi: 10.1002/cne.10776. J Comp Neurol. 2003. PMID: 12926013

2

Wild-type huntingtin plays a role in brain development and neuronal survival.

Reiner A, Dragatsis I, Zeitlin S, Goldowitz D. Reiner A, et al. Among authors: dragatsis i. Mol Neurobiol. 2003 Dec;28(3):259-76. doi: 10.1385/MN:28:3:259. Mol Neurobiol. 2003. PMID: 14709789 Review.

3

Huntingtin-associated protein 1 (Hap1) mutant mice bypassing the early postnatal lethality are neuroanatomically normal and fertile but display growth retardation.

Dragatsis I, Zeitlin S, Dietrich P. Dragatsis I, et al. Hum Mol Genet. 2004 Dec 15;13(24):3115-25. doi: 10.1093/hmg/ddh328. Epub 2004 Oct 20. Hum Mol Genet. 2004. PMID: 15496430

4

Inactivation of Hdh in the brain and testis results in progressive neurodegeneration and sterility in mice.

Dragatsis I, Levine MS, Zeitlin S. Dragatsis I, et al. Nat Genet. 2000 Nov;26(3):300-6. doi: 10.1038/81593. Nat Genet. 2000. PMID: 11062468

5

Mouse mutant embryos lacking huntingtin are rescued from lethality by wild-type extraembryonic tissues.

Dragatsis I, Efstratiadis A, Zeitlin S. Dragatsis I, et al. Development. 1998 Apr;125(8):1529-39. doi: 10.1242/dev.125.8.1529. Development. 1998. PMID: 9502734

6

Elucidating a normal function of huntingtin by functional and microarray analysis of huntingtin-null mouse embryonic fibroblasts.

Zhang H, Das S, Li QZ, Dragatsis I, Repa J, Zeitlin S, Hajnóczky G, Bezprozvanny I. Zhang H, et al. Among authors: dragatsis i. BMC Neurosci. 2008 Apr 15;9:38. doi: 10.1186/1471-2202-9-38. BMC Neurosci. 2008. PMID: 18412970 Free PMC article.

7

Huntingtin is required for normal excitatory synapse development in cortical and striatal circuits.

McKinstry SU, Karadeniz YB, Worthington AK, Hayrapetyan VY, Ozlu MI, Serafin-Molina K, Risher WC, Ustunkaya T, Dragatsis I, Zeitlin S, Yin HH, Eroglu C. McKinstry SU, et al. Among authors: dragatsis i. J Neurosci. 2014 Jul 9;34(28):9455-72. doi: 10.1523/JNEUROSCI.4699-13.2014. J Neurosci. 2014. PMID: 25009276 Free PMC article.

8

A method for the generation of conditional gene repair mutations in mice.

Dragatsis I, Zeitlin S. Dragatsis I, et al. Nucleic Acids Res. 2001 Feb 1;29(3):E10. doi: 10.1093/nar/29.3.e10. Nucleic Acids Res. 2001. PMID: 11160912 Free PMC article.

9

Mutant huntingtin impairs axonal trafficking in mammalian neurons in vivo and in vitro.

Trushina E, Dyer RB, Badger JD 2nd, Ure D, Eide L, Tran DD, Vrieze BT, Legendre-Guillemin V, McPherson PS, Mandavilli BS, Van Houten B, Zeitlin S, McNiven M, Aebersold R, Hayden M, Parisi JE, Seeberg E, Dragatsis I, Doyle K, Bender A, Chacko C, McMurray CT. Trushina E, et al. Among authors: dragatsis i. Mol Cell Biol. 2004 Sep;24(18):8195-209. doi: 10.1128/MCB.24.18.8195-8209.2004. Mol Cell Biol. 2004. PMID: 15340079 Free PMC article.

10

Striatal Projection Neurons Require Huntingtin for Synaptic Connectivity and Survival.

Burrus CJ, McKinstry SU, Kim N, Ozlu MI, Santoki AV, Fang FY, Ma A, Karadeniz YB, Worthington AK, Dragatsis I, Zeitlin S, Yin HH, Eroglu C. Burrus CJ, et al. Among authors: dragatsis i. Cell Rep. 2020 Jan 21;30(3):642-657.e6. doi: 10.1016/j.celrep.2019.12.069. Cell Rep. 2020. PMID: 31968243 Free PMC article.

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