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Defective cholesterol metabolism in haematopoietic stem cells promotes monocyte-driven atherosclerosis in rheumatoid arthritis.
Dragoljevic D, Kraakman MJ, Nagareddy PR, Ngo D, Shihata W, Kammoun HL, Whillas A, Lee MKS, Al-Sharea A, Pernes G, Flynn MC, Lancaster GI, Febbraio MA, Chin-Dusting J, Hanaoka BY, Wicks IP, Murphy AJ. Dragoljevic D, et al. Eur Heart J. 2018 Jun 14;39(23):2158-2167. doi: 10.1093/eurheartj/ehy119. Eur Heart J. 2018. PMID: 29905812 Free PMC article.
Adipose tissue macrophages promote myelopoiesis and monocytosis in obesity.
Nagareddy PR, Kraakman M, Masters SL, Stirzaker RA, Gorman DJ, Grant RW, Dragoljevic D, Hong ES, Abdel-Latif A, Smyth SS, Choi SH, Korner J, Bornfeldt KE, Fisher EA, Dixit VD, Tall AR, Goldberg IJ, Murphy AJ. Nagareddy PR, et al. Among authors: dragoljevic d. Cell Metab. 2014 May 6;19(5):821-35. doi: 10.1016/j.cmet.2014.03.029. Cell Metab. 2014. PMID: 24807222 Free PMC article.
Compound 21, a selective agonist of angiotensin AT2 receptors, prevents endothelial inflammation and leukocyte adhesion in vitro and in vivo.
Sampson AK, Irvine JC, Shihata WA, Dragoljevic D, Lumsden N, Huet O, Barnes T, Unger T, Steckelings UM, Jennings GL, Widdop RE, Chin-Dusting JP. Sampson AK, et al. Among authors: dragoljevic d. Br J Pharmacol. 2016 Feb;173(4):729-40. doi: 10.1111/bph.13063. Epub 2015 Jun 29. Br J Pharmacol. 2016. PMID: 25560767 Free PMC article.
IL-18 Production from the NLRP1 Inflammasome Prevents Obesity and Metabolic Syndrome.
Murphy AJ, Kraakman MJ, Kammoun HL, Dragoljevic D, Lee MK, Lawlor KE, Wentworth JM, Vasanthakumar A, Gerlic M, Whitehead LW, DiRago L, Cengia L, Lane RM, Metcalf D, Vince JE, Harrison LC, Kallies A, Kile BT, Croker BA, Febbraio MA, Masters SL. Murphy AJ, et al. Among authors: dragoljevic d. Cell Metab. 2016 Jan 12;23(1):155-64. doi: 10.1016/j.cmet.2015.09.024. Epub 2015 Oct 22. Cell Metab. 2016. PMID: 26603191 Free article.
Neutrophil-derived S100 calcium-binding proteins A8/A9 promote reticulated thrombocytosis and atherogenesis in diabetes.
Kraakman MJ, Lee MK, Al-Sharea A, Dragoljevic D, Barrett TJ, Montenont E, Basu D, Heywood S, Kammoun HL, Flynn M, Whillas A, Hanssen NM, Febbraio MA, Westein E, Fisher EA, Chin-Dusting J, Cooper ME, Berger JS, Goldberg IJ, Nagareddy PR, Murphy AJ. Kraakman MJ, et al. Among authors: dragoljevic d. J Clin Invest. 2017 Jun 1;127(6):2133-2147. doi: 10.1172/JCI92450. Epub 2017 May 15. J Clin Invest. 2017. PMID: 28504650 Free PMC article.
Leptin-deficient obesity prolongs survival in a murine model of myelodysplastic syndrome.
Kraakman MJ, Kammoun HL, Dragoljevic D, Al-Sharea A, Lee MKS, Flynn MC, Stolz CJ, Guirguis AA, Lancaster GI, Chin-Dusting J, Curtis DJ, Murphy AJ. Kraakman MJ, et al. Among authors: dragoljevic d. Haematologica. 2018 Apr;103(4):597-606. doi: 10.3324/haematol.2017.181958. Epub 2018 Jan 25. Haematologica. 2018. PMID: 29371326 Free PMC article.
Hand of FATe: lipid metabolism in hematopoietic stem cells.
Lee MKS, Al-Sharea A, Dragoljevic D, Murphy AJ. Lee MKS, et al. Among authors: dragoljevic d. Curr Opin Lipidol. 2018 Jun;29(3):240-245. doi: 10.1097/MOL.0000000000000500. Curr Opin Lipidol. 2018. PMID: 29528857 Review.
27 results