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The effect of ABT-761, a novel 5-lipoxygenase inhibitor, on exercise- and adenosine-induced bronchoconstriction in asthmatic subjects.
Am J Respir Crit Care Med. 1997 Mar;155(3):875-80. doi: 10.1164/ajrccm.155.3.9117020.
Am J Respir Crit Care Med. 1997.
PMID: 9117020
Clinical Trial.
Pharmacokinetics and pharmacodynamics of single and multiple oral doses of a novel 5-lipoxygenase inhibitor (ABT-761) in healthy volunteers.
Wong SL, Drajesk J, Chang M, Lanni C, Witt G, Hansen R, Awni WM.
Wong SL, et al.
Clin Pharmacol Ther. 1998 Mar;63(3):324-31. doi: 10.1016/S0009-9236(98)90164-3.
Clin Pharmacol Ther. 1998.
PMID: 9542476
Clinical Trial.
Item in Clipboard
Dose-proportional pharmacokinetics of a new 5-lipoxygenase inhibitor, ABT-761, in healthy volunteers.
Wong SL, Drajesk J, Chang MS, Witt G, Awni WM.
Wong SL, et al.
Biopharm Drug Dispos. 1998 Apr;19(3):159-62. doi: 10.1002/(sici)1099-081x(199804)19:3<159::aid-bdd80>3.0.co;2-o.
Biopharm Drug Dispos. 1998.
PMID: 9569998
Clinical Trial.
Item in Clipboard
Pharmacokinetics of a novel 5-lipoxygenase inhibitor (ABT-761) in pediatric patients with asthma.
Wong SL, Kearns GL, Kemp JP, Drajesk J, Chang M, Locke CS, Dube LM, Awni WM.
Wong SL, et al.
Eur J Clin Pharmacol. 1998 Nov-Dec;54(9-10):715-9. doi: 10.1007/s002280050540.
Eur J Clin Pharmacol. 1998.
PMID: 9923573
Clinical Trial.
Item in Clipboard
Pharmacokinetics of zileuton and its metabolites in patients with renal impairment.
Awni WM, Wong S, Chu SY, Patterson K, Hansen R, Machinist JM, Drajesk J, Keane WF, Halstenson CE.
Awni WM, et al.
J Clin Pharmacol. 1997 May;37(5):395-404. doi: 10.1002/j.1552-4604.1997.tb04317.x.
J Clin Pharmacol. 1997.
PMID: 9156372
Clinical Trial.
Item in Clipboard
Pharmacogenetic association between ALOX5 promoter genotype and the response to anti-asthma treatment.
Drazen JM, Yandava CN, Dubé L, Szczerback N, Hippensteel R, Pillari A, Israel E, Schork N, Silverman ES, Katz DA, Drajesk J.
Drazen JM, et al.
Nat Genet. 1999 Jun;22(2):168-70. doi: 10.1038/9680.
Nat Genet. 1999.
PMID: 10369259
Clinical Trial.
Item in Clipboard
Clinical observation of liver chemistry abnormalities in asthmatics.
Katz DA, Isaacson JD, Han L, Drajesk JF, Comer GM, Heath-Chiozzi ME.
Katz DA, et al. Among authors: drajesk jf.
Curr Drug Saf. 2009 Sep;4(3):173-80. doi: 10.2174/157488609789006930. Epub 2009 Sep 1.
Curr Drug Saf. 2009.
PMID: 19534645
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