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Too many mutants with multiple mutations.
Drake JW. Drake JW. Crit Rev Biochem Mol Biol. 2007 Jul-Aug;42(4):247-58. doi: 10.1080/10409230701495631. Crit Rev Biochem Mol Biol. 2007. PMID: 17687667 Free PMC article. Review.
Clusters of mutations from transient hypermutability.
Drake JW, Bebenek A, Kissling GE, Peddada S. Drake JW, et al. Proc Natl Acad Sci U S A. 2005 Sep 6;102(36):12849-54. doi: 10.1073/pnas.0503009102. Epub 2005 Aug 23. Proc Natl Acad Sci U S A. 2005. PMID: 16118275 Free PMC article.
General antimutators are improbable.
Drake JW. Drake JW. J Mol Biol. 1993 Jan 5;229(1):8-13. doi: 10.1006/jmbi.1993.1002. J Mol Biol. 1993. PMID: 8421317
Mutations in clusters and showers.
Drake JW. Drake JW. Proc Natl Acad Sci U S A. 2007 May 15;104(20):8203-4. doi: 10.1073/pnas.0703089104. Epub 2007 May 10. Proc Natl Acad Sci U S A. 2007. PMID: 17495029 Free PMC article. No abstract available.
Rates of spontaneous mutation.
Drake JW, Charlesworth B, Charlesworth D, Crow JF. Drake JW, et al. Genetics. 1998 Apr;148(4):1667-86. doi: 10.1093/genetics/148.4.1667. Genetics. 1998. PMID: 9560386 Free PMC article. Review.
114 results