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IAP inhibitors enhance co-stimulation to promote tumor immunity.
Dougan M, Dougan S, Slisz J, Firestone B, Vanneman M, Draganov D, Goyal G, Li W, Neuberg D, Blumberg R, Hacohen N, Porter D, Zawel L, Dranoff G. Dougan M, et al. Among authors: dranoff g. J Exp Med. 2010 Sep 27;207(10):2195-206. doi: 10.1084/jem.20101123. Epub 2010 Sep 13. J Exp Med. 2010. PMID: 20837698 Free PMC article.
Vaccination with irradiated autologous melanoma cells engineered to secrete human granulocyte-macrophage colony-stimulating factor generates potent antitumor immunity in patients with metastatic melanoma.
Soiffer R, Lynch T, Mihm M, Jung K, Rhuda C, Schmollinger JC, Hodi FS, Liebster L, Lam P, Mentzer S, Singer S, Tanabe KK, Cosimi AB, Duda R, Sober A, Bhan A, Daley J, Neuberg D, Parry G, Rokovich J, Richards L, Drayer J, Berns A, Clift S, Cohen LK, Mulligan RC, Dranoff G. Soiffer R, et al. Among authors: dranoff g. Proc Natl Acad Sci U S A. 1998 Oct 27;95(22):13141-6. doi: 10.1073/pnas.95.22.13141. Proc Natl Acad Sci U S A. 1998. PMID: 9789055 Free PMC article. Clinical Trial.
Vaccination with irradiated autologous tumor cells engineered to secrete granulocyte-macrophage colony-stimulating factor augments antitumor immunity in some patients with metastatic non-small-cell lung carcinoma.
Salgia R, Lynch T, Skarin A, Lucca J, Lynch C, Jung K, Hodi FS, Jaklitsch M, Mentzer S, Swanson S, Lukanich J, Bueno R, Wain J, Mathisen D, Wright C, Fidias P, Donahue D, Clift S, Hardy S, Neuberg D, Mulligan R, Webb I, Sugarbaker D, Mihm M, Dranoff G. Salgia R, et al. Among authors: dranoff g. J Clin Oncol. 2003 Feb 15;21(4):624-30. doi: 10.1200/JCO.2003.03.091. J Clin Oncol. 2003. PMID: 12586798 Clinical Trial.
Melanoma inhibitor of apoptosis protein (ML-IAP) is a target for immune-mediated tumor destruction.
Schmollinger JC, Vonderheide RH, Hoar KM, Maecker B, Schultze JL, Hodi FS, Soiffer RJ, Jung K, Kuroda MJ, Letvin NL, Greenfield EA, Mihm M, Kutok JL, Dranoff G. Schmollinger JC, et al. Among authors: dranoff g. Proc Natl Acad Sci U S A. 2003 Mar 18;100(6):3398-403. doi: 10.1073/pnas.0530311100. Epub 2003 Mar 7. Proc Natl Acad Sci U S A. 2003. PMID: 12626761 Free PMC article.
Coordinated tumor immunity.
Dranoff G. Dranoff G. J Clin Invest. 2003 Apr;111(8):1116-8. doi: 10.1172/JCI18359. J Clin Invest. 2003. PMID: 12697728 Free PMC article. No abstract available.
CD1d-restricted T cells regulate dendritic cell function and antitumor immunity in a granulocyte-macrophage colony-stimulating factor-dependent fashion.
Gillessen S, Naumov YN, Nieuwenhuis EE, Exley MA, Lee FS, Mach N, Luster AD, Blumberg RS, Taniguchi M, Balk SP, Strominger JL, Dranoff G, Wilson SB. Gillessen S, et al. Among authors: dranoff g. Proc Natl Acad Sci U S A. 2003 Jul 22;100(15):8874-9. doi: 10.1073/pnas.1033098100. Epub 2003 Jul 7. Proc Natl Acad Sci U S A. 2003. PMID: 12847287 Free PMC article.
221 results