Drasin DJ - Search Results

1

The Six1 oncoprotein downregulates p53 via concomitant regulation of RPL26 and microRNA-27a-3p.

Towers CG, Guarnieri AL, Micalizzi DS, Harrell JC, Gillen AE, Kim J, Wang CA, Oliphant MUJ, Drasin DJ, Guney MA, Kabos P, Sartorius CA, Tan AC, Perou CM, Espinosa JM, Ford HL. Towers CG, et al. Among authors: drasin dj. Nat Commun. 2015 Dec 21;6:10077. doi: 10.1038/ncomms10077. Nat Commun. 2015. PMID: 26687066 Free PMC article.

2

Homeoprotein Six2 promotes breast cancer metastasis via transcriptional and epigenetic control of E-cadherin expression.

Wang CA, Drasin D, Pham C, Jedlicka P, Zaberezhnyy V, Guney M, Li H, Nemenoff R, Costello JC, Tan AC, Ford HL. Wang CA, et al. Cancer Res. 2014 Dec 15;74(24):7357-70. doi: 10.1158/0008-5472.CAN-14-0666. Epub 2014 Oct 27. Cancer Res. 2014. PMID: 25348955 Free PMC article.

3

The miR-106b-25 cluster targets Smad7, activates TGF-β signaling, and induces EMT and tumor initiating cell characteristics downstream of Six1 in human breast cancer.

Smith AL, Iwanaga R, Drasin DJ, Micalizzi DS, Vartuli RL, Tan AC, Ford HL. Smith AL, et al. Among authors: drasin dj. Oncogene. 2012 Dec 13;31(50):5162-71. doi: 10.1038/onc.2012.11. Epub 2012 Jan 30. Oncogene. 2012. PMID: 22286770 Free PMC article.

4

The miR-106b-25 cluster mediates breast tumor initiation through activation of NOTCH1 via direct repression of NEDD4L.

Guarnieri AL, Towers CG, Drasin DJ, Oliphant MUJ, Andrysik Z, Hotz TJ, Vartuli RL, Linklater ES, Pandey A, Khanal S, Espinosa JM, Ford HL. Guarnieri AL, et al. Among authors: drasin dj. Oncogene. 2018 Jul;37(28):3879-3893. doi: 10.1038/s41388-018-0239-7. Epub 2018 Apr 17. Oncogene. 2018. PMID: 29662198 Free PMC article.

5

TWIST1-Induced miR-424 Reversibly Drives Mesenchymal Programming while Inhibiting Tumor Initiation.

Drasin DJ, Guarnieri AL, Neelakantan D, Kim J, Cabrera JH, Wang CA, Zaberezhnyy V, Gasparini P, Cascione L, Huebner K, Tan AC, Ford HL. Drasin DJ, et al. Cancer Res. 2015 May 1;75(9):1908-21. doi: 10.1158/0008-5472.CAN-14-2394. Epub 2015 Feb 25. Cancer Res. 2015. PMID: 25716682 Free PMC article.

6

Breast cancer epithelial-to-mesenchymal transition: examining the functional consequences of plasticity.

Drasin DJ, Robin TP, Ford HL. Drasin DJ, et al. Breast Cancer Res. 2011;13(6):226. doi: 10.1186/bcr3037. Epub 2011 Nov 1. Breast Cancer Res. 2011. PMID: 22078097 Free PMC article. Review.

7

Intratumoral heterogeneity: Clonal cooperation in epithelial-to-mesenchymal transition and metastasis.

Neelakantan D, Drasin DJ, Ford HL. Neelakantan D, et al. Among authors: drasin dj. Cell Adh Migr. 2015;9(4):265-76. doi: 10.4161/19336918.2014.972761. Epub 2014 Oct 16. Cell Adh Migr. 2015. PMID: 25482627 Free PMC article. Review.

8

Allosteric inhibitors of the Eya2 phosphatase are selective and inhibit Eya2-mediated cell migration.

Krueger AB, Drasin DJ, Lea WA, Patrick AN, Patnaik S, Backos DS, Matheson CJ, Hu X, Barnaeva E, Holliday MJ, Blevins MA, Robin TP, Eisenmesser EZ, Ferrer M, Simeonov A, Southall N, Reigan P, Marugan J, Ford HL, Zhao R. Krueger AB, et al. Among authors: drasin dj. J Biol Chem. 2014 Jun 6;289(23):16349-61. doi: 10.1074/jbc.M114.566729. Epub 2014 Apr 22. J Biol Chem. 2014. PMID: 24755226 Free PMC article.

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