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XLF and APLF bind Ku80 at two remote sites to ensure DNA repair by non-homologous end joining.
Nemoz C, Ropars V, Frit P, Gontier A, Drevet P, Yu J, Guerois R, Pitois A, Comte A, Delteil C, Barboule N, Legrand P, Baconnais S, Yin Y, Tadi S, Barbet-Massin E, Berger I, Le Cam E, Modesti M, Rothenberg E, Calsou P, Charbonnier JB. Nemoz C, et al. Among authors: drevet p. Nat Struct Mol Biol. 2018 Oct;25(10):971-980. doi: 10.1038/s41594-018-0133-6. Epub 2018 Oct 5. Nat Struct Mol Biol. 2018. PMID: 30291363 Free PMC article.
C-terminal region of bacterial Ku controls DNA bridging, DNA threading and recruitment of DNA ligase D for double strand breaks repair.
McGovern S, Baconnais S, Roblin P, Nicolas P, Drevet P, Simonson H, Piétrement O, Charbonnier JB, Le Cam E, Noirot P, Lecointe F. McGovern S, et al. Among authors: drevet p. Nucleic Acids Res. 2016 Jun 2;44(10):4785-4806. doi: 10.1093/nar/gkw149. Epub 2016 Mar 9. Nucleic Acids Res. 2016. PMID: 26961308 Free PMC article.
Structural characterization of filaments formed by human Xrcc4-Cernunnos/XLF complex involved in nonhomologous DNA end-joining.
Ropars V, Drevet P, Legrand P, Baconnais S, Amram J, Faure G, Márquez JA, Piétrement O, Guerois R, Callebaut I, Le Cam E, Revy P, de Villartay JP, Charbonnier JB. Ropars V, et al. Among authors: drevet p. Proc Natl Acad Sci U S A. 2011 Aug 2;108(31):12663-8. doi: 10.1073/pnas.1100758108. Epub 2011 Jul 18. Proc Natl Acad Sci U S A. 2011. PMID: 21768349 Free PMC article.
Delineation of the Xrcc4-interacting region in the globular head domain of cernunnos/XLF.
Malivert L, Ropars V, Nunez M, Drevet P, Miron S, Faure G, Guerois R, Mornon JP, Revy P, Charbonnier JB, Callebaut I, de Villartay JP. Malivert L, et al. Among authors: drevet p. J Biol Chem. 2010 Aug 20;285(34):26475-83. doi: 10.1074/jbc.M110.138156. Epub 2010 Jun 17. J Biol Chem. 2010. PMID: 20558749 Free PMC article.
32 results