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Microtubule affinity-regulating kinase 2 functions downstream of the PAR-3/PAR-6/atypical PKC complex in regulating hippocampal neuronal polarity.
Chen YM, Wang QJ, Hu HS, Yu PC, Zhu J, Drewes G, Piwnica-Worms H, Luo ZG. Chen YM, et al. Among authors: drewes g. Proc Natl Acad Sci U S A. 2006 May 30;103(22):8534-9. doi: 10.1073/pnas.0509955103. Epub 2006 May 22. Proc Natl Acad Sci U S A. 2006. PMID: 16717194 Free PMC article.
Comprehensive proteomic analysis of human Par protein complexes reveals an interconnected protein network.
Brajenovic M, Joberty G, Küster B, Bouwmeester T, Drewes G. Brajenovic M, et al. Among authors: drewes g. J Biol Chem. 2004 Mar 26;279(13):12804-11. doi: 10.1074/jbc.M312171200. Epub 2003 Dec 15. J Biol Chem. 2004. PMID: 14676191
MARKing tau for tangles and toxicity.
Drewes G. Drewes G. Trends Biochem Sci. 2004 Oct;29(10):548-55. doi: 10.1016/j.tibs.2004.08.001. Trends Biochem Sci. 2004. PMID: 15450610 Review.
Proteome survey reveals modularity of the yeast cell machinery.
Gavin AC, Aloy P, Grandi P, Krause R, Boesche M, Marzioch M, Rau C, Jensen LJ, Bastuck S, Dümpelfeld B, Edelmann A, Heurtier MA, Hoffman V, Hoefert C, Klein K, Hudak M, Michon AM, Schelder M, Schirle M, Remor M, Rudi T, Hooper S, Bauer A, Bouwmeester T, Casari G, Drewes G, Neubauer G, Rick JM, Kuster B, Bork P, Russell RB, Superti-Furga G. Gavin AC, et al. Among authors: drewes g. Nature. 2006 Mar 30;440(7084):631-6. doi: 10.1038/nature04532. Epub 2006 Jan 22. Nature. 2006. PMID: 16429126
Global approaches to protein-protein interactions.
Drewes G, Bouwmeester T. Drewes G, et al. Curr Opin Cell Biol. 2003 Apr;15(2):199-205. doi: 10.1016/s0955-0674(03)00005-x. Curr Opin Cell Biol. 2003. PMID: 12648676 Review.
Glycogen synthase kinase-3 and the Alzheimer-like state of microtubule-associated protein tau.
Mandelkow EM, Drewes G, Biernat J, Gustke N, Van Lint J, Vandenheede JR, Mandelkow E. Mandelkow EM, et al. Among authors: drewes g. FEBS Lett. 1992 Dec 21;314(3):315-21. doi: 10.1016/0014-5793(92)81496-9. FEBS Lett. 1992. PMID: 1334849
Interactions of MAP/microtubule affinity regulating kinases with the adaptor complex AP-2 of clathrin-coated vesicles.
Schmitt-Ulms G, Matenia D, Drewes G, Mandelkow EM. Schmitt-Ulms G, et al. Among authors: drewes g. Cell Motil Cytoskeleton. 2009 Aug;66(8):661-72. doi: 10.1002/cm.20394. Cell Motil Cytoskeleton. 2009. PMID: 19536824
MARK [microtubule-associated proteins (MAPs)/microtubule affinity regulating kinase]/Par-1 (partition defective) phosphorylate MAPs tau, MAP2 and MAP4 at KXGS motifs and thereby regulate microtubule dynamics and transport processes in cells [Drewes et al., Cell1997;89:297- …
MARK [microtubule-associated proteins (MAPs)/microtubule affinity regulating kinase]/Par-1 (partition defective) phosphorylate MAPs tau, MAP …
Microtubule-affinity regulating kinase (MARK) is tightly associated with neurofibrillary tangles in Alzheimer brain: a fluorescence resonance energy transfer study.
Chin JY, Knowles RB, Schneider A, Drewes G, Mandelkow EM, Hyman BT. Chin JY, et al. Among authors: drewes g. J Neuropathol Exp Neurol. 2000 Nov;59(11):966-71. doi: 10.1093/jnen/59.11.966. J Neuropathol Exp Neurol. 2000. PMID: 11089574
Proteomics-based strategies in kinase drug discovery.
Bantscheff M, Hopf C, Kruse U, Drewes G. Bantscheff M, et al. Among authors: drewes g. Ernst Schering Found Symp Proc. 2007;(3):1-28. doi: 10.1007/2789_2007_060. Ernst Schering Found Symp Proc. 2007. PMID: 18512284 Review.
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