Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 2
2001 1
2002 5
2003 7
2004 9
2005 3
2006 4
2007 7
2008 5
2009 11
2010 8
2011 2
2012 2
2013 8
2014 8
2015 10
2016 3
2017 7
2018 4
2019 3
2020 9
2021 17
2022 10
2023 5
2024 2
2025 1

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

15 results

Results by year

Filters applied: from 2000/1/1 - 2003/12/12. Clear all
Page 1
Newly discovered coronavirus as the primary cause of severe acute respiratory syndrome.
Kuiken T, Fouchier RA, Schutten M, Rimmelzwaan GF, van Amerongen G, van Riel D, Laman JD, de Jong T, van Doornum G, Lim W, Ling AE, Chan PK, Tam JS, Zambon MC, Gopal R, Drosten C, van der Werf S, Escriou N, Manuguerra JC, Stöhr K, Peiris JS, Osterhaus AD. Kuiken T, et al. Lancet. 2003 Jul 26;362(9380):263-70. doi: 10.1016/S0140-6736(03)13967-0. Lancet. 2003. PMID: 12892955 Free PMC article.
SARS-CoV was detected in pneumonic areas by virus isolation and RT-PCR, and was localised to alveolar epithelial cells and syncytia by immunohistochemistry and transmission electron microscopy. ...
SARS-CoV was detected in pneumonic areas by virus isolation and RT-PCR, and was localised to alveolar epithelial cells and syncytia b …
Detection and quantification of Mycobacterium leprae in tissue samples by real-time PCR.
Kramme S, Bretzel G, Panning M, Kawuma J, Drosten C. Kramme S, et al. Med Microbiol Immunol. 2004 Nov;193(4):189-93. doi: 10.1007/s00430-003-0188-8. Epub 2003 Jul 22. Med Microbiol Immunol. 2004. PMID: 12884037
Real-time PCR technology has improved molecular diagnostics of many pathogens, but no such test is available for Mycobacterium leprae. ...Real-time detection thus did not increase the clinical sensitivity of PCR as compared to conventional protocols, in spite of its …
Real-time PCR technology has improved molecular diagnostics of many pathogens, but no such test is available for Mycobacterium leprae …
Murine susceptibility to Chagas' disease maps to chromosomes 5 and 17.
Graefe SE, Meyer BS, Müller-Myhsok B, Rüschendorf F, Drosten C, Laue T, Steeg C, Nürnberg P, Fleischer B. Graefe SE, et al. Genes Immun. 2003 Jul;4(5):321-5. doi: 10.1038/sj.gene.6363972. Genes Immun. 2003. PMID: 12847546
We quantified parasite tissue burdens in resistant and susceptible strains by real time PCR and applied a backcross strategy to map the genomic loci linked to susceptibility in inbred mice. ...
We quantified parasite tissue burdens in resistant and susceptible strains by real time PCR and applied a backcross strategy to map t …
Identification of a novel coronavirus in patients with severe acute respiratory syndrome.
Drosten C, Günther S, Preiser W, van der Werf S, Brodt HR, Becker S, Rabenau H, Panning M, Kolesnikova L, Fouchier RA, Berger A, Burguière AM, Cinatl J, Eickmann M, Escriou N, Grywna K, Kramme S, Manuguerra JC, Müller S, Rickerts V, Stürmer M, Vieth S, Klenk HD, Osterhaus AD, Schmitz H, Doerr HW. Drosten C, et al. N Engl J Med. 2003 May 15;348(20):1967-76. doi: 10.1056/NEJMoa030747. Epub 2003 Apr 10. N Engl J Med. 2003. PMID: 12690091 Free article.
The virus was isolated in cell culture, and a sequence 300 nucleotides in length was obtained by a polymerase-chain-reaction (PCR)-based random-amplification procedure. Genetic characterization indicated that the virus is only distantly related to known coronaviruses (iden …
The virus was isolated in cell culture, and a sequence 300 nucleotides in length was obtained by a polymerase-chain-reaction (PCR)-ba …
Detection, differentiation, and quantitation of pathogenic leishmania organisms by a fluorescence resonance energy transfer-based real-time PCR assay.
Schulz A, Mellenthin K, Schönian G, Fleischer B, Drosten C. Schulz A, et al. J Clin Microbiol. 2003 Apr;41(4):1529-35. doi: 10.1128/JCM.41.4.1529-1535.2003. J Clin Microbiol. 2003. PMID: 12682141 Free PMC article.
Real-time technology eliminates many of the pitfalls of diagnostic PCR, but this method has not been applied to differentiation of Leishmania organisms so far. ...Therefore, despite its superior analytical performance, care must be taken when real-time PCR is utiliz …
Real-time technology eliminates many of the pitfalls of diagnostic PCR, but this method has not been applied to differentiation of Le …
Molecular diagnostics of viral hemorrhagic fevers.
Drosten C, Kümmerer BM, Schmitz H, Günther S. Drosten C, et al. Antiviral Res. 2003 Jan;57(1-2):61-87. doi: 10.1016/s0166-3542(02)00201-2. Antiviral Res. 2003. PMID: 12615304 Review.
Currently available polymerase chain reaction (PCR) assays for diagnosis of VHF are summarized and discussed. In the second part, VHF diagnostics are described in particular for Lassa fever, yellow fever, and Crimean-Congo hemorrhagic fever, based on cases that were import …
Currently available polymerase chain reaction (PCR) assays for diagnosis of VHF are summarized and discussed. In the second part, VHF …
NAT for HBV and anti-HBc testing increase blood safety.
Roth WK, Weber M, Petersen D, Drosten C, Buhr S, Sireis W, Weichert W, Hedges D, Seifried E. Roth WK, et al. Transfusion. 2002 Jul;42(7):869-75. doi: 10.1046/j.1537-2995.2002.00128.x. Transfusion. 2002. PMID: 12375659
Retesting by single-sample PCR of 432 samples confirmed positive for HBsAg identified 37 donations that were negative in minipool PCR. ...After testing randomly selected 729 HBsAg-negative minipool PCR-negative, anti-HBc-positive donors by single-sample enric …
Retesting by single-sample PCR of 432 samples confirmed positive for HBsAg identified 37 donations that were negative in minipool …
Yield of HCV and HIV-1 NAT after screening of 3.6 million blood donations in central Europe.
Roth WK, Weber M, Buhr S, Drosten C, Weichert W, Sireis W, Hedges D, Seifried E. Roth WK, et al. Transfusion. 2002 Jul;42(7):862-8. doi: 10.1046/j.1537-2995.2002.00129.x. Transfusion. 2002. PMID: 12375658
To compensate for dilution of the individual donor samples by pooling, viruses were enriched from the pools by centrifugation at 48,000 x g. A commercial PCR (Cobas Amplicor, Roche) and an in-house PCR were applied for HCV and HIV-1 amplification, respectively. ...L …
To compensate for dilution of the individual donor samples by pooling, viruses were enriched from the pools by centrifugation at 48,000 x g. …
15 results