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The receptor tyrosine kinase c-Kit controls IL-33 receptor signaling in mast cells.
Drube S, Heink S, Walter S, Löhn T, Grusser M, Gerbaulet A, Berod L, Schons J, Dudeck A, Freitag J, Grotha S, Reich D, Rudeschko O, Norgauer J, Hartmann K, Roers A, Kamradt T. Drube S, et al. Blood. 2010 May 13;115(19):3899-906. doi: 10.1182/blood-2009-10-247411. Epub 2010 Mar 3. Blood. 2010. PMID: 20200353
Subthreshold IKK activation modulates the effector functions of primary mast cells and allows specific targeting of transformed mast cells.
Drube S, Weber F, Loschinski R, Beyer M, Rothe M, Rabenhorst A, Göpfert C, Meininger I, Diamanti MA, Stegner D, Häfner N, Böttcher M, Reinecke K, Herdegen T, Greten FR, Nieswandt B, Hartmann K, Krämer OH, Kamradt T. Drube S, et al. Oncotarget. 2015 Mar 10;6(7):5354-68. doi: 10.18632/oncotarget.3022. Oncotarget. 2015. PMID: 25749030 Free PMC article.
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