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32 results

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Page 1
Drug-induced olfactory and gustatory dysfunction: Analysis of FDA adverse events reporting system.
Debbaneh P, McKinnon L, Haidari M, Liang J. Debbaneh P, et al. Auris Nasus Larynx. 2023 Aug;50(4):558-564. doi: 10.1016/j.anl.2022.12.012. Epub 2023 Jan 20. Auris Nasus Larynx. 2023. PMID: 36682949
OBJECTIVES: With the COVID-19 pandemic, there is growing interest and research in olfactory and gustatory dysfunction (OGD). Drug-induced dysfunction is an often overlooked etiology. ...We identified the top reported medications associated with …
OBJECTIVES: With the COVID-19 pandemic, there is growing interest and research in olfactory and gustatory dysfunction (OGD). …
Comparative Olfactory Profiles in Parkinson's Disease and Drug-Induced Parkinsonism.
Kwak IH, Kim YE, Kang SY, Lee JS, Lee J, Kim MS, Yea DA, Ma HI. Kwak IH, et al. J Mov Disord. 2024 Jan;17(1):64-70. doi: 10.14802/jmd.23105. Epub 2023 Oct 6. J Mov Disord. 2024. PMID: 37798852 Free PMC article.
While olfactory dysfunction is a common clinical feature in PD, the comparison of olfactory function between the two conditions remains insufficient. ...CONCLUSION: This study demonstrated that detailed olfactory profiles are different in PD and DIP, e …
While olfactory dysfunction is a common clinical feature in PD, the comparison of olfactory function between the two co …
Early-onset drug-induced parkinsonism after exposure to offenders implies nigrostriatal dopaminergic dysfunction.
Chung SJ, Yoo HS, Moon H, Oh JS, Kim JS, Park YH, Hong JY, Ye BS, Sohn YH, Lee PH. Chung SJ, et al. J Neurol Neurosurg Psychiatry. 2018 Feb;89(2):169-174. doi: 10.1136/jnnp-2017-315873. Epub 2017 Sep 14. J Neurol Neurosurg Psychiatry. 2018. PMID: 28912301
OBJECTIVES: The onset of parkinsonism in patients with drug-induced parkinsonism (DIP) exhibits extensive individual variability following exposure to offending drugs. ...CONCLUSIONS: These results suggest that a short exposure to the offending drugs before the deve …
OBJECTIVES: The onset of parkinsonism in patients with drug-induced parkinsonism (DIP) exhibits extensive individual variabili …
Neuroleptic-induced parkinsonism is associated with olfactory dysfunction.
Krüger S, Haehner A, Thiem C, Hummel T. Krüger S, et al. J Neurol. 2008 Oct;255(10):1574-9. doi: 10.1007/s00415-008-0993-5. Epub 2008 Sep 3. J Neurol. 2008. PMID: 18769856
OBJECTIVE: There is increasing evidence for olfactory deficits in patients with extrapyramidal disorders, but little is known about their occurrence in patients with drug-induced extrapyramidal symptoms (EPS). The present study was performed to investigate …
OBJECTIVE: There is increasing evidence for olfactory deficits in patients with extrapyramidal disorders, but little is known about t …
Drug-induced taste and smell disorders. Incidence, mechanisms and management related primarily to treatment of sensory receptor dysfunction.
Henkin RI. Henkin RI. Drug Saf. 1994 Nov;11(5):318-77. doi: 10.2165/00002018-199411050-00004. Drug Saf. 1994. PMID: 7873092 Review.
Drugs in every major pharmacological category can impair both taste and smell function and do so more commonly than presently appreciated. Impairment usually affects sensory function at a molecular level, causing 2 major behavioural changes--loss of acuity (i.e. hypogeusia …
Drugs in every major pharmacological category can impair both taste and smell function and do so more commonly than presently appreci …
Relationship between the severity of olfactory dysfunction and serum zinc levels.
Tanaka H, Mori E, Sekine R, Yonezawa N, Tei M, Otori N. Tanaka H, et al. Eur Arch Otorhinolaryngol. 2023 Jul;280(7):3229-3236. doi: 10.1007/s00405-023-07828-x. Epub 2023 Feb 10. Eur Arch Otorhinolaryngol. 2023. PMID: 36763150
We investigated the relationship between serum zinc levels and olfactory function in patients with olfactory dysfunction. METHODS: Ninety patients who had been diagnosed with post-infectious, posttraumatic, drug-induced, neurological and idiopat …
We investigated the relationship between serum zinc levels and olfactory function in patients with olfactory dysfunction
Functional and Morphological Changes in the Olfactory Epithelium of Mouse Models With Upper Respiratory Inflammation and Olfactory Dysfunction.
Yoo SH, Bae JS, Ventura R, Kim EH, Kim AY, Kim JH, Mo JH. Yoo SH, et al. Clin Exp Otorhinolaryngol. 2025 Nov;18(4):349-360. doi: 10.21053/ceo.2025-00003. Epub 2025 May 26. Clin Exp Otorhinolaryngol. 2025. PMID: 40419279 Free PMC article.
Olfactory function was evaluated using an open-field food-finding test and a T-maze test one week after model induction. ...CONCLUSION: This study demonstrated significant differences in olfactory function and histological changes among various mouse models of upper
Olfactory function was evaluated using an open-field food-finding test and a T-maze test one week after model induction. ...CONCLUSIO
The status of olfactory function and the striatal dopaminergic system in drug-induced parkinsonism.
Bovi T, Antonini A, Ottaviani S, Antonioli A, Cecchini MP, Di Francesco V, Bassetto MA, Zamboni M, Fiaschi A, Moretto G, Sbarbati A, Osculati F, Tinazzi M. Bovi T, et al. J Neurol. 2010 Nov;257(11):1882-9. doi: 10.1007/s00415-010-5631-3. Epub 2010 Jul 16. J Neurol. 2010. PMID: 20635186 Free article.
Olfactory impairment has been reported in drug-induced parkinsonism (DIP), but the relationship between dopaminergic dysfunction and smell deficits in DIP patients has not been characterized. ...Nineteen healthy age- and sex-matched subjects ser
Olfactory impairment has been reported in drug-induced parkinsonism (DIP), but the relationship between dopaminergic
Brain mechanisms of drug-induced reinforcement.
Kornetsky C, Porrino LJ. Kornetsky C, et al. Res Publ Assoc Res Nerv Ment Dis. 1992;70:59-77. Res Publ Assoc Res Nerv Ment Dis. 1992. PMID: 1311122 Review.
The major effects are found in the nucleus accumbens, olfactory tubercle, and the medial prefrontal cortex. Cocaine produces increases in metabolic rates similar in distribution to BSR. ...These findings suggest that the olfactory tubercle plays a major role in the …
The major effects are found in the nucleus accumbens, olfactory tubercle, and the medial prefrontal cortex. Cocaine produces increase …
Motor and non-motor features of Parkinson's disease that predict persistent drug-induced Parkinsonism.
Morley JF, Pawlowski SM, Kesari A, Maina I, Pantelyat A, Duda JE. Morley JF, et al. Parkinsonism Relat Disord. 2014 Jul;20(7):738-42. doi: 10.1016/j.parkreldis.2014.03.024. Epub 2014 Apr 1. Parkinsonism Relat Disord. 2014. PMID: 24742370
Additionally, drug-induced Parkinsonism may, in some cases, represent "unmasking" of incipient Parkinson's disease. ...CONCLUSIONS: A constellation of motor and non-motor features may differentiate unmasked Parkinson's disease from drug-induced Parkins …
Additionally, drug-induced Parkinsonism may, in some cases, represent "unmasking" of incipient Parkinson's disease. ...CONCLUS …
32 results