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Leads for the development of neuroprotective treatment in Parkinson's disease and brain imaging methods for estimating treatment efficacy.
Stoof JC, Winogrodzka A, van Muiswinkel FL, Wolters EC, Voorn P, Groenewegen HJ, Booij J, Drukarch B. Stoof JC, et al. Among authors: Drukarch B. Eur J Pharmacol. 1999 Jun 30;375(1-3):75-86. doi: 10.1016/s0014-2999(99)00260-5. Eur J Pharmacol. 1999. PMID: 10443566 Review.
Enhanced sensitivity of dopaminergic neurons to rotenone-induced toxicity with aging.
Phinney AL, Andringa G, Bol JG, Wolters ECh, van Muiswinkel FL, van Dam AM, Drukarch B. Phinney AL, et al. Among authors: Drukarch B. Parkinsonism Relat Disord. 2006 May;12(4):228-38. doi: 10.1016/j.parkreldis.2005.12.002. Epub 2006 Feb 20. Parkinsonism Relat Disord. 2006. PMID: 16488175
NAD(P)H:quinone oxidoreductase 1 expression in multiple sclerosis lesions.
van Horssen J, Schreibelt G, Bö L, Montagne L, Drukarch B, van Muiswinkel FL, de Vries HE. van Horssen J, et al. Among authors: Drukarch B. Free Radic Biol Med. 2006 Jul 15;41(2):311-7. doi: 10.1016/j.freeradbiomed.2006.04.013. Epub 2006 Apr 26. Free Radic Biol Med. 2006. PMID: 16814112
Neuroinflammation in Parkinson's patients and MPTP-treated mice is not restricted to the nigrostriatal system: microgliosis and differential expression of interleukin-1 receptors in the olfactory bulb.
Vroon A, Drukarch B, Bol JG, Cras P, Brevé JJ, Allan SM, Relton JK, Hoogland PV, Van Dam AM. Vroon A, et al. Among authors: Drukarch B. Exp Gerontol. 2007 Aug;42(8):762-71. doi: 10.1016/j.exger.2007.04.010. Epub 2007 Apr 29. Exp Gerontol. 2007. PMID: 17592750
Nrf2-induced antioxidant protection: a promising target to counteract ROS-mediated damage in neurodegenerative disease?
de Vries HE, Witte M, Hondius D, Rozemuller AJ, Drukarch B, Hoozemans J, van Horssen J. de Vries HE, et al. Among authors: Drukarch B. Free Radic Biol Med. 2008 Nov 15;45(10):1375-83. doi: 10.1016/j.freeradbiomed.2008.09.001. Epub 2008 Sep 13. Free Radic Biol Med. 2008. PMID: 18824091 Review.
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