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52 results

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Page 1
LSD1 inhibition ameliorates congenital dyserythropoietic anemia type II.
Yu L, Wang Y, King R, Myers G, Deng K, McGee B, Friedman A, Balbin-Cuesta G, Lin Z, Drysdale C, Liu X, Min JC, Kerpet C, Guan Y, Gallagher PJ, Ozel AB, Robida A, Engel JD, Khoriaty R. Yu L, et al. Among authors: drysdale c. Sci Transl Med. 2026 Mar 25;18(842):eadt4859. doi: 10.1126/scitranslmed.adt4859. Epub 2026 Mar 25. Sci Transl Med. 2026. PMID: 41880517
Lipid metabolism transcriptomic signature of defective erythropoiesis in Diamond Blackfan anemia syndrome.
Deng K, Wang Y, Min JC, Liu X, Ueharu H, Myers G, Yu L, Hammoud S, Adam A, Saba R, Natogi V, Drysdale C, Chen B, Yee J, Kitzman JO, Lyssiotis CA, Mishina Y, Jones M, Kaartinen V, Guan Y, Khoriaty R, Engel JD, Singh SA. Deng K, et al. Among authors: drysdale c. Blood Adv. 2026 Apr 14;10(7):2272-2285. doi: 10.1182/bloodadvances.2025017318. Blood Adv. 2026. PMID: 41576344 Free PMC article.
p27Kip1 regulates γ-globin production.
Balbin-Cuesta G, Drysdale C, Kerpet C, Yu L, Myers G, Lin Z, McGee B, Friedman A, Liu X, Singh SA, Engel JD, Buttitta L, Khoriaty R. Balbin-Cuesta G, et al. Among authors: drysdale c. Blood. 2026 Feb 26;147(9):973-986. doi: 10.1182/blood.2025028895. Blood. 2026. PMID: 41411145 Free PMC article.
A lipid metabolism defect is an underlying contributor to Diamond Blackfan anemia syndrome.
Deng K, Wang Y, Min JC, Liu X, Myers G, Yu L, Hammoud S, Adam A, Saba R, Natogi V, Drysdale C, Chen B, Ueharu H, Yee JL, Kitzman J, Lyssiotis CA, Mishina Y, Jones M, Kaartinen V, Guan Y, Khoriaty R, Engel JD, Singh SA. Deng K, et al. Among authors: drysdale c. bioRxiv [Preprint]. 2025 May 27:2025.05.22.654334. doi: 10.1101/2025.05.22.654334. bioRxiv. 2025. PMID: 40502144 Free PMC article. Preprint.
A genome-wide screen identifies genes required for erythroid differentiation.
Myers G, Friedman A, Yu L, Pourmandi N, Kerpet C, Ito MA, Saba R, Tang V, Ozel AB, Bergin IL, Johnson CN, Ku CJ, Wang Y, Balbin-Cuesta G, Lim KC, Lin Z, Drysdale C, McGee B, Kurita R, Nakamura Y, Liu X, Siemieniak D, Singh SA, Lyssiotis CA, Maillard I, Weisman LS, Engel JD, Khoriaty R. Myers G, et al. Among authors: drysdale c. Nat Commun. 2025 Apr 12;16(1):3488. doi: 10.1038/s41467-025-58739-w. Nat Commun. 2025. PMID: 40221460 Free PMC article.
Clearance and transport of amyloid β by peripheral monocytes correlate with Alzheimer's disease progression.
Huang X, Fowler C, Li Y, Li QX, Sun J, Pan Y, Jin L, Perez KA, Dubois C, Lim YY, Drysdale C, Rumble RL, Chinnery HR, Rowe CC, Martins RN, Maruff P, Doecke JD, Lin Y, Belaidi AA, Barnham KJ, Masters CL, Gu BJ. Huang X, et al. Among authors: drysdale c. Nat Commun. 2024 Sep 12;15(1):7998. doi: 10.1038/s41467-024-52396-1. Nat Commun. 2024. PMID: 39266542 Free PMC article.
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